Title:
TETRAVALENT PLATINUM-CONTAINING COMPLEX, PRODRUG, PREPARATION METHOD THEREFOR, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/041532
Kind Code:
A1
Abstract:
The present disclosure relates to a complex comprising a tetravalent platinum moiety and an oligopeptide as an axial ligand chemically linked to the platinum.
Inventors:
SHI KAI (CN)
BI HONGSHU (CN)
BI HONGSHU (CN)
Application Number:
PCT/CN2023/114257
Publication Date:
February 29, 2024
Filing Date:
August 22, 2023
Export Citation:
Assignee:
GANZHOU HEMAY PHARMACEUTICAL CO LTD (CN)
International Classes:
C07K5/093; A61K38/06; A61P35/00; B82Y5/00; B82Y40/00; C07K1/107
Foreign References:
| CN115368436A | 2022-11-22 | |||
| CN105622674A | 2016-06-01 | |||
| CN101591377A | 2009-12-02 | |||
| US20210023129A1 | 2021-01-28 |
Other References:
ZHANG WEI-QIANG, WANG CHEN, ZHAO YU-RONG, WANG DONG, WANG JI-QIAN, XU HAI: "Research Progress of Regulation of Driving Forces in Short Peptide Supramolecular Self-Assembly", CHINESE JOURNAL OF APPLIED CHEMISTRY., vol. 39, no. 8, 10 August 2022 (2022-08-10), pages 1190 - 1201, XP093143270, DOI: 10.19894/j.issn.1000-0518.210507
JIA CHUNYAN; DEACON GLEN B.; ZHANG YINGJIE; GAO CHUANZHU: "Platinum(IV) antitumor complexes and their nano-drug delivery", COORDINATION CHEMISTRY REVIEWS, ELSEVIER SCIENCE, AMSTERDAM., NL, vol. 429, 25 November 2020 (2020-11-25), NL , XP086442108, ISSN: 0010-8545, DOI: 10.1016/j.ccr.2020.213640
SUMITRA MUKHOPADHYAY, CARMEN M. BARNÉS, ARIEL HASKEL, SARAH M. SHORT, KATIE R. BARNES, STEPHEN J. LIPPARD: "Conjugated Platinum(IV)−Peptide Complexes for Targeting Angiogenic Tumor Vasculature", BIOCONJUGATE CHEMISTRY, AMERICAN CHEMICAL SOCIETY, vol. 19, no. 1, 1 January 2008 (2008-01-01), pages 39 - 49, XP055104575, ISSN: 10431802, DOI: 10.1021/bc070031k
JIA CHUNYAN; DEACON GLEN B.; ZHANG YINGJIE; GAO CHUANZHU: "Platinum(IV) antitumor complexes and their nano-drug delivery", COORDINATION CHEMISTRY REVIEWS, ELSEVIER SCIENCE, AMSTERDAM., NL, vol. 429, 25 November 2020 (2020-11-25), NL , XP086442108, ISSN: 0010-8545, DOI: 10.1016/j.ccr.2020.213640
SUMITRA MUKHOPADHYAY, CARMEN M. BARNÉS, ARIEL HASKEL, SARAH M. SHORT, KATIE R. BARNES, STEPHEN J. LIPPARD: "Conjugated Platinum(IV)−Peptide Complexes for Targeting Angiogenic Tumor Vasculature", BIOCONJUGATE CHEMISTRY, AMERICAN CHEMICAL SOCIETY, vol. 19, no. 1, 1 January 2008 (2008-01-01), pages 39 - 49, XP055104575, ISSN: 10431802, DOI: 10.1021/bc070031k
Attorney, Agent or Firm:
INSIGHT INTELLECTUAL PROPERTY LTD. (CN)
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