Title:
TGF-β INHIBITOR COMPOUND AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/032598
Kind Code:
A1
Abstract:
The present application relates to a TGF-β inhibitor compound and the use thereof. Specifically, disclosed in the present application is a compound as represented by formula (I), or an isotope-labeled compound thereof, or an optical isomer, a geometric isomer, a tautomer or an isomer mixture thereof, or a pharmaceutically acceptable salt thereof, or a prodrug thereof, or a metabolite thereof. The present application also relates to the use of the compound in medicine.
Inventors:
LU LIANG (CN)
ZHAO SAISAI (CN)
ZHANG LONGZHENG (CN)
HUANG HAI (CN)
ZHANG JIXUAN (CN)
ZHU JUNJIE (CN)
WANG XIAOLONG (CN)
CHEN JIAXIN (CN)
LING SHANCUN (CN)
LIAO XINWEI (CN)
ZHAO SAISAI (CN)
ZHANG LONGZHENG (CN)
HUANG HAI (CN)
ZHANG JIXUAN (CN)
ZHU JUNJIE (CN)
WANG XIAOLONG (CN)
CHEN JIAXIN (CN)
LING SHANCUN (CN)
LIAO XINWEI (CN)
Application Number:
PCT/CN2023/111704
Publication Date:
February 15, 2024
Filing Date:
August 08, 2023
Export Citation:
Assignee:
HENAN MEDINNO PHARMACEUTICAL TECH CO LTD (CN)
International Classes:
C07D487/04; A61K31/4188; A61P35/00; C07D471/04; C07D519/00
Domestic Patent References:
| WO2021027594A1 | 2021-02-18 |
Foreign References:
| CN112341477A | 2021-02-09 | |||
| CN114380818A | 2022-04-22 | |||
| CN111606908A | 2020-09-01 | |||
| CN114075200A | 2022-02-22 | |||
| CN114524818A | 2022-05-24 |
Attorney, Agent or Firm:
BEIJING EAST IP LTD. (CN)
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