Title:
THERAPEUTIC AGENT FOR DISEASES MEDIATED BY MICROSPORIDIA AND MYXOSPOREA BOTH PARASITIC IN MARINE FISHES
Document Type and Number:
WIPO Patent Application WO/2018/062246
Kind Code:
A1
Abstract:
Provided is a method for controlling microsporidia or myxosporea in marine fishes (particularly cultured fishes) with an oral administration agent. A control agent for "Beko" disease or a myxosporean disease mediated by microsporidia parasitic in marine fishes, said controlling agent containing, as an active ingredient, any one of albendazole, febantel, flubendazole, fenbendazole, oxfendazole and mebendazole.
Inventors:
HIRAZAWA NORITAKA (JP)
AKIYAMA KOUSUKE (JP)
AKIYAMA KOUSUKE (JP)
Application Number:
PCT/JP2017/034901
Publication Date:
April 05, 2018
Filing Date:
September 27, 2017
Export Citation:
Assignee:
NIPPON SUISAN KAISHA LTD (JP)
KUROSE SUISAN CO LTD (JP)
KUROSE SUISAN CO LTD (JP)
International Classes:
A61K31/4184; A61K31/27; A61P33/00
Foreign References:
| JP2017186306A | 2017-10-12 |
Other References:
SALEH, M. ET AL.: "Development of a novel in vitro method for drug development for fish; application to test efficacy of antimicrosporidian compounds", VETERINARY RECORD, vol. 175, no. 22, 6 December 2014 (2014-12-06) - 15 September 2016 (2016-09-15), pages 561, XP055603006, ISSN: 0042-4900, DOI: 10.1136/vr.102604
KUMAR, G. ET AL.: "In vitro cultivation model for Heterosporis saurida (Microsporidia) isolated from lizardfish, Saurida undosquamis (Richardson", JOURNAL OF FISH DISEASES, vol. 37, no. 5, 20 August 2013 (2013-08-20) - May 2014 (2014-05-01), pages 443 - 449, XP055603008, ISSN: 0140-7775, DOI: 10.1111/jfd.12123
SPEARE, D. J. ET AL.: "A preliminary investigation of alternatives to fumagillin for the treatment of Loma salmonae infection in rainbow trout", J. COMP. PATH., vol. 121, no. 3, 1999, pages 241 - 248, XP008050193, DOI: doi:10.1053/jcpa.1999.0325
SCHMAHL, G. ET AL.: "Treatment of fish parasites. 11. Effects of different benzimidazole derivatives (albendazole, mebendazole, fenbendazole) on Glugea anomala, Moniez. 1887 (Microsporidia): ultrastructural aspects and efficacy studies", PARASITOL. RES., vol. 84, no. 1, February 1998 (1998-02-01), pages 41 - 49, XP055578950
HIROSHI YASUDA ET AL.: "Torafugu no Yasebyo no bojo chiryoho ni kansuru kenkyu, Heisei 12 Nendo Gyobyo Taisaku Gijutsu Kaihatsu Kenkyu Seika Hokokusho", JAPAN FISHERIES RESOURCE CONSERVATION ASSOCIATION, 2001, pages 25 - 30
KUMAR, G. ET AL.: "In vitro cultivation model for Heterosporis saurida (Microsporidia) isolated from lizardfish, Saurida undosquamis (Richardson", JOURNAL OF FISH DISEASES, vol. 37, no. 5, 20 August 2013 (2013-08-20) - May 2014 (2014-05-01), pages 443 - 449, XP055603008, ISSN: 0140-7775, DOI: 10.1111/jfd.12123
SPEARE, D. J. ET AL.: "A preliminary investigation of alternatives to fumagillin for the treatment of Loma salmonae infection in rainbow trout", J. COMP. PATH., vol. 121, no. 3, 1999, pages 241 - 248, XP008050193, DOI: doi:10.1053/jcpa.1999.0325
SCHMAHL, G. ET AL.: "Treatment of fish parasites. 11. Effects of different benzimidazole derivatives (albendazole, mebendazole, fenbendazole) on Glugea anomala, Moniez. 1887 (Microsporidia): ultrastructural aspects and efficacy studies", PARASITOL. RES., vol. 84, no. 1, February 1998 (1998-02-01), pages 41 - 49, XP055578950
HIROSHI YASUDA ET AL.: "Torafugu no Yasebyo no bojo chiryoho ni kansuru kenkyu, Heisei 12 Nendo Gyobyo Taisaku Gijutsu Kaihatsu Kenkyu Seika Hokokusho", JAPAN FISHERIES RESOURCE CONSERVATION ASSOCIATION, 2001, pages 25 - 30
Attorney, Agent or Firm:
ONO, Shinjiro et al. (JP)
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