Title:
THERAPEUTIC AGENT FOR FIBROMYALGIA WHICH COMPRISES DONEPEZIL
Document Type and Number:
WIPO Patent Application WO/2013/115083
Kind Code:
A1
Abstract:
[Problem] The purpose of the present invention is to provide a medicinal agent effective for the treatment of fibromyalgia.
[Solution] The present invention relates to a therapeutic agent for fibromyalgia, which comprises an effective amount of donepezil or a pharmaceutically acceptable salt of donepezil as an active ingredient. Pain associated with fibromyalgia is not accompanied by any inflammation, and therefore there is not found any good amelioration method for the pain. Thus, the present invention provides a pain-ameliorating agent that is extremely effective for patients with the pain.
Inventors:
UEDA HIROSHI (JP)
Application Number:
PCT/JP2013/051547
Publication Date:
August 08, 2013
Filing Date:
January 25, 2013
Export Citation:
Assignee:
SHIN NIPPON BIOMEDICAL LAB LTD (JP)
UNIV NAGASAKI (JP)
UNIV NAGASAKI (JP)
International Classes:
A61K31/445; A61P25/04
Domestic Patent References:
| WO2000015205A2 | 2000-03-23 | |||
| WO2006086698A2 | 2006-08-17 |
Other References:
MUKAE,T. ET AL.: "Donepezil causes permanent pain relief in mouse experimental fibromyalgia model", JOURNAL OF PHARMACOLOGICAL SCIENCES, vol. 118, March 2012 (2012-03-01), pages 97P
TAKEHIRO MUKAE ET AL.: "Noshitsunai Pregabalin Oyobi Zenshinsei Donepezil no Kurikaeshi Toyo ga Sen'ikintsusho Model Mouse no Mansei Totsu o Kanchi Saseru", PAIN RESEARCH, vol. 27, no. 2, July 2012 (2012-07-01), pages 101
TAKEHIRO MUKAE ET AL.: "Noshitsunai Pregabalin Oyobi Zenshinsei Donepezil no Kurikaeshi Toyo ga Sen'ikintsusho Model Mouse no Mansei Totsu o Kanchi Saseru", PAIN RESEARCH, vol. 27, no. 2, July 2012 (2012-07-01), pages 101
Attorney, Agent or Firm:
HIROSE TAKAYUKI (JP)
Takayuki Hirose (JP)
Takayuki Hirose (JP)
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Claims: