Title:
THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR FIBROMYALGIA
Document Type and Number:
WIPO Patent Application WO/2011/125836
Kind Code:
A1
Abstract:
Disclosed is a therapeutic agent or prophylactic agent that has analgesic effects on both nociceptive pain and neuropathic pain and is effective in the treatment of fibromyalgia. Specifically disclosed is a therapeutic agent or prophylactic agent for fibromyalgia that includes, as an active component, a cyclohexane derivative represented by the formula, or a pharmaceutically acceptable salt or prodrug thereof.
Inventors:
YOSHIDA CHIHIRO (JP)
NAKAO KAORU (JP)
NAKAO KAORU (JP)
Application Number:
PCT/JP2011/058218
Publication Date:
October 13, 2011
Filing Date:
March 31, 2011
Export Citation:
Assignee:
TORAY INDUSTRIES (JP)
YOSHIDA CHIHIRO (JP)
NAKAO KAORU (JP)
YOSHIDA CHIHIRO (JP)
NAKAO KAORU (JP)
International Classes:
C07D231/12; A61K31/415; A61K31/421; A61K31/426; A61K31/4439; A61P21/00; A61P25/02; A61P25/04; C07D263/32; C07D277/24; C07D401/04
Domestic Patent References:
| WO2000066562A1 | 2000-11-09 | |||
| WO2007111323A1 | 2007-10-04 | |||
| WO2008105383A1 | 2008-09-04 | |||
| WO2008105383A1 | 2008-09-04 | |||
| WO2000066562A1 | 2000-11-09 | |||
| WO2007111323A1 | 2007-10-04 |
Foreign References:
| JP2002526442A | 2002-08-20 | |||
| JP2002525361A | 2002-08-13 |
Other References:
See also references of EP 2554541A4
WOLFE ET AL., ARTHRITIS RHEUM., vol. 33, 1990, pages 160
NICKERSON B, US PHARMA., vol. 34, 2009, pages 49
ABELES ET AL., AM J MED., vol. 121, 2008, pages 555
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 39, 1989, pages 393 - 395
"PROTECTIVE GROUPS IN ORGANIC SYNTHESIS", WILEY-INTERSCIENCE
TETRAHEDRON, vol. 45, 1989, pages 5703 - 5742
TETRAHEDRON LETTERS, vol. 47, 2006, pages 1729 - 1731
"Iyakuhin no Kaihatsu", vol. 7, 1990, HIROKAWA SHOTEN, pages: 163 - 198
PROG. MED., vol. 5, 1985, pages 2157 - 2161
SLUKA ET AL., J. PHARMACOL. EXP. THER., vol. 302, 2002, pages 1146
NAGAKURA ET AL., PAIN, vol. 146, 2009, pages 26
SLUKA ET AL., PAIN, vol. 146, 2009, pages 3
CHAPLAN ET AL., J. NEUROSCI. METHODS, vol. 53, 1994, pages 55
MALMBERG, PAIN, vol. 76, 1998, pages 215 - 222
WOLFE ET AL., ARTHRITIS RHEUM., vol. 33, 1990, pages 160
NICKERSON B, US PHARMA., vol. 34, 2009, pages 49
ABELES ET AL., AM J MED., vol. 121, 2008, pages 555
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 39, 1989, pages 393 - 395
"PROTECTIVE GROUPS IN ORGANIC SYNTHESIS", WILEY-INTERSCIENCE
TETRAHEDRON, vol. 45, 1989, pages 5703 - 5742
TETRAHEDRON LETTERS, vol. 47, 2006, pages 1729 - 1731
"Iyakuhin no Kaihatsu", vol. 7, 1990, HIROKAWA SHOTEN, pages: 163 - 198
PROG. MED., vol. 5, 1985, pages 2157 - 2161
SLUKA ET AL., J. PHARMACOL. EXP. THER., vol. 302, 2002, pages 1146
NAGAKURA ET AL., PAIN, vol. 146, 2009, pages 26
SLUKA ET AL., PAIN, vol. 146, 2009, pages 3
CHAPLAN ET AL., J. NEUROSCI. METHODS, vol. 53, 1994, pages 55
MALMBERG, PAIN, vol. 76, 1998, pages 215 - 222
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