Title:
THERAPEUTIC AGENT AND TEST AGENT FOR DISEASE WITH MYOCARDIAL NECROSIS
Document Type and Number:
WIPO Patent Application WO/2010/007701
Kind Code:
A1
Abstract:
Disclosed are a pharmaceutical for treating or preventing a disease with myocardial necrosis containing, as an active ingredient, a periostin variant (ΔbΔe) polypeptide or a modified form thereof or a polynucleotide encoding the same; and a test agent for a disease with myocardial necrosis containing a DNA encoding a periostin variant (ΔbΔe) polypeptide or a partial fragment thereof or an antibody which specifically recognizes a periostin variant (ΔbΔe) polypeptide.
Inventors:
KUDO, Akira (4259 Nagatsuta-cho, Midori-ku, Yokohama-sh, Kanagawa 01, 22685, JP)
Application Number:
JP2008/072743
Publication Date:
January 21, 2010
Filing Date:
December 15, 2008
Export Citation:
Assignee:
TOKYO INSTITUTE OF TECHNOLOGY (2-12-1, Ookayama Meguro-k, Tokyo 50, 15285, JP)
国立大学法人東京工業大学 (〒50 東京都目黒区大岡山２丁目１２番１号 Tokyo, 15285, JP)
Mitsubishi Chemical Medience Corporation (2-8 Shibaura 4-chome, Minato-ku Tokyo, 59, 10885, JP)
国立大学法人東京工業大学 (〒50 東京都目黒区大岡山２丁目１２番１号 Tokyo, 15285, JP)
Mitsubishi Chemical Medience Corporation (2-8 Shibaura 4-chome, Minato-ku Tokyo, 59, 10885, JP)
International Classes:
A61K38/00; A61K31/7088; A61K39/395; A61K48/00; A61P9/10; C07K16/18; C12Q1/02; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; C07K14/47; C12N15/09
Attorney, Agent or Firm:
MORITA, Kenichi et al. (5th Fl, Itabashi-chuo Bldg.67-8, Itabashi 2-chom, Itabashi-ku Tokyo 04, 17300, JP)