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Patent Searching and Data


Title:
THERAPEUTIC COMBINATIONS FOR CARDIOVASCULAR AND INFLAMMATORY INDICATIONS
Document Type and Number:
WIPO Patent Application WO2002078625
Kind Code:
A3
Abstract:
The present invention provides therapeutic combinations and methods for treating or preventing a hypercholesterolemia-related or an inflammation -related condition in a subject in need of such treatment or prevention. One therapeutic combination comprises an ASBT inhibitor combined with COX-2 inhibitor. A further therapeutic combination comprises an ASBT inhibitor, a COX-2 inhibitor and an HMG Co-A reductase inhibitor. Another therapeutic combination comprises a chromene COX-2 inhibitor and an HMG Co-A reductase inhibitor.

Inventors:
SEIBERT KAREN (US)
KELLER BRADLEY T (US)
ISAKSON PETER C (US)
Application Number:
US0209185W
Publication Date:
March 13, 2003
Filing Date:
March 27, 2002
Export Citation:
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Assignee:
PHARMACIA CORPORATION
SEIBERT, KAREN
KELLER, BRADLEY, T.
ISAKSON, PETER, C.
International Classes:
C07D237/14; A61K31/10; A61K31/18; A61K31/19; A61K31/196; A61K31/216; A61K31/22; A61K31/352; A61K31/365; A61K31/366; A61K31/38; A61K31/381; A61K31/382; A61K31/40; A61K31/404; A61K31/405; A61K31/415; A61K31/42; A61K31/421; A61K31/426; A61K31/437; A61K31/44; A61K31/4418; A61K31/4436; A61K31/444; A61K31/47; A61K31/50; A61K31/505; A61K31/535; A61K31/5377; A61K31/554; A61K31/77; A61K45/06; A61P1/04; A61P1/16; A61P1/18; A61P3/06; A61P9/00; A61P9/10; A61P19/06; A61P29/00; C07D207/34; C07D209/24; C07D213/34; C07D213/55; C07D213/61; C07D213/64; C07D213/85; C07D215/12; C07D231/12; C07D239/42; C07D261/08; C07D263/32; C07D265/02; C07D277/10; C07D277/20; C07D277/54; C07D281/10; C07D307/58; C07D309/30; C07D311/22; C07D311/58; C07D311/80; C07D311/92; C07D311/96; C07D333/36; C07D335/06; C07D337/08; C07D401/04; C07D403/06; C07D417/04; C07D471/04; C07D487/08; (IPC1-7): A61K31/38; A61K31/35; A61K31/21; A61K31/54
Foreign References:
US6020347A2000-02-01
US6147090A2000-11-14
US6077850A2000-06-20
US5994391A1999-11-30
US5932598A1999-08-03
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