Title:
THERAPEUTIC DRUG FOR AUTOIMMUNE DISEASE
Document Type and Number:
WIPO Patent Application WO/2012/157746
Kind Code:
A1
Abstract:
The present invention provides a screening method for a preventive or therapeutic agent for an autoimmune disease, comprising evaluating agonist activity or antagonist activity of a test compound on a lysophosphatidylserine receptor using P2Y10 or GPR174.
Inventors:
AOKI JUNKEN (JP)
MAKIDE KUMIKO (JP)
INOUE ASUKA (JP)
OHWADA TOMOHIKO (JP)
IKUBO MASAYA (JP)
OTANI YUKO (JP)
MAKIDE KUMIKO (JP)
INOUE ASUKA (JP)
OHWADA TOMOHIKO (JP)
IKUBO MASAYA (JP)
OTANI YUKO (JP)
Application Number:
PCT/JP2012/062782
Publication Date:
November 22, 2012
Filing Date:
May 18, 2012
Export Citation:
Assignee:
UNIV TOHOKU (JP)
UNIV TOKYO (JP)
AOKI JUNKEN (JP)
MAKIDE KUMIKO (JP)
INOUE ASUKA (JP)
OHWADA TOMOHIKO (JP)
IKUBO MASAYA (JP)
OTANI YUKO (JP)
UNIV TOKYO (JP)
AOKI JUNKEN (JP)
MAKIDE KUMIKO (JP)
INOUE ASUKA (JP)
OHWADA TOMOHIKO (JP)
IKUBO MASAYA (JP)
OTANI YUKO (JP)
International Classes:
G01N33/50; A61K31/661; A61P1/16; A61P5/14; A61P21/00; A61P21/04; A61P25/00; A61P29/00; A61P37/02; A61P37/06; C07F9/09; C12Q1/02; G01N33/15
Domestic Patent References:
| WO2004047758A2 | 2004-06-10 |
Foreign References:
| JPH05124978A | 1993-05-21 | |||
| JP2010184867A | 2010-08-26 | |||
| JP2007284402A | 2007-11-01 | |||
| JP2007267601A | 2007-10-18 |
Other References:
MICHIYO OKUTANI ET AL., SEIKAGAKU, August 2011 (2011-08-01), pages 3T8P-18
HONMA, Y ET AL., CANCER RESEARCH, vol. 41, 1981, pages 3211 - 3216
TOMORI-NATORI, Y. ET AL., J. BIOCHEM., vol. 100, 1986, pages 581 - 590
IWASHIMA, M. ET AL., J. MED. CHEM., vol. 52, 2009, pages 5837 - 5863
JUN ISHIGURO ET AL.: "Shishitsu Seikagaku Kenkyu", vol. 52, 2010, pages 221 - 224
MURAKAMI, M. ET AL., BIOCHEMICAL AND BIOPHYSICAL RESEACH COMMUNICATIONS, vol. 371, 2008, pages 707 - 712
HAJIME KITAMURA ET AL., JOURNAL OF JAPANESE BIOCHEMICAL SOCIETY, 2008, pages 3T18-7
HAJIME KITAMURA ET AL., JOURNAL OF JAPANESE BIOCHEMICAL SOCIETY, 2009, pages 2T20P-4
HONMA, Y ET AL., CANCER RESEARCH, vol. 41, 1981, pages 3211 - 3216
TOMORI-NATORI, Y. ET AL., J. BIOCHEM., vol. 100, 1986, pages 581 - 590
IWASHIMA, M. ET AL., J. MED. CHEM., vol. 52, 2009, pages 5837 - 5863
JUN ISHIGURO ET AL.: "Shishitsu Seikagaku Kenkyu", vol. 52, 2010, pages 221 - 224
MURAKAMI, M. ET AL., BIOCHEMICAL AND BIOPHYSICAL RESEACH COMMUNICATIONS, vol. 371, 2008, pages 707 - 712
HAJIME KITAMURA ET AL., JOURNAL OF JAPANESE BIOCHEMICAL SOCIETY, 2008, pages 3T18-7
HAJIME KITAMURA ET AL., JOURNAL OF JAPANESE BIOCHEMICAL SOCIETY, 2009, pages 2T20P-4
Attorney, Agent or Firm:
ONO, Shinjiro et al. (JP)
Ono Shinjiro (JP)
Ono Shinjiro (JP)
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