Title:
THERAPEUTIC ENGINEERED MICROBIAL CELL SYSTEMS AND METHODS FOR TREATING HYPERURICEMIA AND GOUT
Document Type and Number:
WIPO Patent Application WO/2021/142491
Kind Code:
A2
Abstract:
The present disclosure relates to engineered microbial cells that have been engineered to include a uricase, a uric acid transporter, or both a uricase and a uric acid transporter. The engineered microbial cells of the present disclosure are useful in degrading uric acid inside the engineered microbial cell. The engineered microbial cells of the present disclosure are useful in methods of treating hyperuricemia. The engineered microbial cells of the present disclosure are also useful in methods of treating gout, and in particular chronic refractory gout.
Inventors:
GEISLER CHRISTOPH (US)
Application Number:
PCT/US2021/070014
Publication Date:
July 15, 2021
Filing Date:
January 08, 2021
Export Citation:
Assignee:
THERANEUTRICS LLC (US)
International Classes:
A61B34/30
Attorney, Agent or Firm:
HIBBS, Genna, S. (US)
Download PDF:
Previous Patent: BLOOD PUMP WITH IMPROVED LEAKAGE CONTROL
Next Patent: MODIFIED DOWNLINK CONTROL INFORMATION TO SUPPORT LOW TIER USER EQUIPMENT
Next Patent: MODIFIED DOWNLINK CONTROL INFORMATION TO SUPPORT LOW TIER USER EQUIPMENT