Title:
THERAPEUTIC PEPTIDES
Document Type and Number:
WIPO Patent Application WO/2018/164019
Kind Code:
A1
Abstract:
The present invention provides peptides, salts thereof, peptide conjugates, and salts thereof having an anxiolytic-like effect, for example a peptide comprising any amino acid sequence selected from (i) an amino acid sequence SYLPPLTT (SEQ ID NO: 1), (ii) an amino acid sequence YHIEPV (SEQ ID NO: 2), (iii) an amino acid sequence YLLVK (SEQ ID NO: 3), (iv)an amino acid sequence SYLPPLT (SEQ ID NO: 4), (v) an amino acid sequence FLLVK (SEQ ID NO: 5), and (vi) an amino acid sequence WLLVK (SEQ ID NO: 6).
More Like This:
| WO/2010/112711 | NOVEL PROTEASOME-ACTIVATING LIGHTENING PEPTIDES AND COMPOSITIONS CONTAINING SAME |
| JP2003000242 | CYTOTOXIC T LYMPHOCYTE |
| WO/2005/123767 | PEPTIDE-BASED COMPOUNDS |
Inventors:
OHINATA KOUSAKU (JP)
KIMURA SAEKO (JP)
SUZUKI HIDEYUKI (JP)
KIMURA SAEKO (JP)
SUZUKI HIDEYUKI (JP)
Application Number:
PCT/JP2018/008183
Publication Date:
September 13, 2018
Filing Date:
March 02, 2018
Export Citation:
Assignee:
UNIV KYOTO (JP)
KAZUSA DNA RES INSTITUTE (JP)
KAZUSA DNA RES INSTITUTE (JP)
International Classes:
C07K7/06; A23L33/18; A23L33/185; A61K38/00; C07K5/087; C07K5/10; C07K7/08
Domestic Patent References:
| WO2011135527A2 | 2011-11-03 | |||
| WO2011148972A1 | 2011-12-01 |
Foreign References:
| JP2009242335A | 2009-10-22 | |||
| EP2740796A1 | 2014-06-11 |
Other References:
YUN HAE JIN ET AL: "Isolation and Characterization of a cDNA for a Ribulose-1,5-Bisphophate Carboxylase Small Subunit in Spinach", JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY, vol. 30, no. 3, 31 May 1997 (1997-05-31), pages 173 - 176, XP009505479
HIRATA ET AL: "Rubiscolin-6, a delta opioid peptide derived from spinach Rubisco, has anxiolytic effect via activating sigma1 and dopamine D1 receptors", PEPTIDES, ELSEVIER, AMSTERDAM, NL, vol. 28, no. 10, 20 September 2007 (2007-09-20), pages 1998 - 2003, XP022261276, ISSN: 0196-9781, DOI: 10.1016/J.PEPTIDES.2007.07.024
MASAAKI YOSHIKAWA: "Bioactive peptides derived from natural proteins with respect to diversity of their receptors and physiological effects", PEPTIDES, vol. 72, 1 October 2015 (2015-10-01), AMSTERDAM, NL, pages 208 - 225, XP055424806, ISSN: 0196-9781, DOI: 10.1016/j.peptides.2015.07.013
ZHAO HUI ET AL: "Rubimetide, humanin, and MMK1 exert anxiolytic-like activities via the formyl peptide receptor 2 in mice followed by the successive activation of DP1, A2A, and GABAAreceptors", PEPTIDES, ELSEVIER, AMSTERDAM, NL, vol. 83, 27 July 2016 (2016-07-27), pages 16 - 20, XP029682947, ISSN: 0196-9781, DOI: 10.1016/J.PEPTIDES.2016.07.001
ARTEMOVA N V ET AL: "Opioid peptides derived from food proteins suppress aggregation and promote reactivation of partly unfolded stressed proteins", PEPTIDES, ELSEVIER, AMSTERDAM, NL, vol. 31, no. 2, 1 February 2010 (2010-02-01), pages 332 - 338, XP026854142, ISSN: 0196-9781, [retrieved on 20091130]
HIRATA ET AL: "Rubiscolin-6, a delta opioid peptide derived from spinach Rubisco, has anxiolytic effect via activating sigma1 and dopamine D1 receptors", PEPTIDES, ELSEVIER, AMSTERDAM, NL, vol. 28, no. 10, 20 September 2007 (2007-09-20), pages 1998 - 2003, XP022261276, ISSN: 0196-9781, DOI: 10.1016/J.PEPTIDES.2007.07.024
MASAAKI YOSHIKAWA: "Bioactive peptides derived from natural proteins with respect to diversity of their receptors and physiological effects", PEPTIDES, vol. 72, 1 October 2015 (2015-10-01), AMSTERDAM, NL, pages 208 - 225, XP055424806, ISSN: 0196-9781, DOI: 10.1016/j.peptides.2015.07.013
ZHAO HUI ET AL: "Rubimetide, humanin, and MMK1 exert anxiolytic-like activities via the formyl peptide receptor 2 in mice followed by the successive activation of DP1, A2A, and GABAAreceptors", PEPTIDES, ELSEVIER, AMSTERDAM, NL, vol. 83, 27 July 2016 (2016-07-27), pages 16 - 20, XP029682947, ISSN: 0196-9781, DOI: 10.1016/J.PEPTIDES.2016.07.001
ARTEMOVA N V ET AL: "Opioid peptides derived from food proteins suppress aggregation and promote reactivation of partly unfolded stressed proteins", PEPTIDES, ELSEVIER, AMSTERDAM, NL, vol. 31, no. 2, 1 February 2010 (2010-02-01), pages 332 - 338, XP026854142, ISSN: 0196-9781, [retrieved on 20091130]
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
Download PDF:
Previous Patent: SLOTTED PATCH ANTENNA
Next Patent: METHOD AND DEVICE FOR MANUFACTURING PROTEIN FIBER
Next Patent: METHOD AND DEVICE FOR MANUFACTURING PROTEIN FIBER