Title:
THERAPEUTIC AND/OR PREVENTIVE AGENT FOR DISEASE ACCOMPANIED BY CELL OVERGROWTH, AND POLYNUCLEOTIDE USEFUL AS THE ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2008/018517
Kind Code:
A1
Abstract:
The invention provides a therapeutic and/or preventive agent for a disease accompanied by
cell overgrowth, particularly a therapeutic and/or preventive agent for the
disease with reduced side effects. More particularly, the invention provides a
therapeutic and/or preventive agent for a disease accompanied by cell overgrowth, containing
a TAK1-specific inhibitor; an siRNA against TAK1 gene; an siRNA expression vector
containing a polynucleotide encoding the siRNA; a pharmaceutical containing the
siRNA or the siRNA expression vector; a cell with reduced proliferative capacity, in
which the expression of TAK1 has been specifically suppressed, or a tissue containing
the cell; and the like.
Inventors:
SETO, Koichi (10-11, Nihonbashi Kobuna-ch, Chuo-ku Tokyo 51, 1038351, JP)
瀬戸 孝一 (〒51 東京都中央区日本橋小舟町１０番１１号 ゼリア新薬工業株式会社内 Tokyo, 1038351, JP)
瀬戸 孝一 (〒51 東京都中央区日本橋小舟町１０番１１号 ゼリア新薬工業株式会社内 Tokyo, 1038351, JP)
Application Number:
JP2007/065553
Publication Date:
February 14, 2008
Filing Date:
August 08, 2007
Export Citation:
Assignee:
ZERIA Pharmaceutical Co., Ltd. (10-11, Nihonbashi Kobuna-choChuo-ku, Tokyo 51, 1038351, JP)
ゼリア新薬工業株式会社 (〒51 東京都中央区日本橋小舟町１０番１１号 Tokyo, 1038351, JP)
SETO, Koichi (10-11, Nihonbashi Kobuna-ch, Chuo-ku Tokyo 51, 1038351, JP)
ゼリア新薬工業株式会社 (〒51 東京都中央区日本橋小舟町１０番１１号 Tokyo, 1038351, JP)
SETO, Koichi (10-11, Nihonbashi Kobuna-ch, Chuo-ku Tokyo 51, 1038351, JP)
International Classes:
A61K45/00; A61K31/7088; A61K48/00; A61P29/00; A61P35/00; C12N5/00; C12N15/00
Attorney, Agent or Firm:
TAKASHIMA, Hajime (Meiji Yasuda Seimei Osaka Midosuji Bldg, 1-1 Fushimimachi 4-chome, Chuo-k, Osaka-shi Osaka 44, 5410044, JP)
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