Title:
THERAPEUTIC OR PROPHYLACTIC AGENT FOR DEMENTIA AND BEHAVIORAL AND PSYCHOLOGICAL SYMPTOMS
Document Type and Number:
WIPO Patent Application WO/2013/168315
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a therapeutic or prophylactic agent for behavioral and psychological symptoms or dementia accompanied by behavioral and psychological symptoms, which does not cause any accessory symptom (adverse side effect) such as accidental aspiration, falling, oversedation, cognitive deterioration and cardiac infarction and does not induce pseudoaldosteronism even when administered for a long period.
A therapeutic or prophylactic agent for dementia, which comprises fluvoxamine or a pharmaceutically acceptable fluvoxamine salt as an active ingredient. A therapeutic or prophylactic agent for dementia accompanied by behavioral and psychological symptoms, which comprises fluvoxamine or a pharmaceutically acceptable fluvoxamine salt as an active ingredient.
Inventors:
KURITA MASATAKE (JP)
NISHINO SATOSHI (JP)
NISHINO SATOSHI (JP)
Application Number:
PCT/JP2012/081189
Publication Date:
November 14, 2013
Filing Date:
November 30, 2012
Export Citation:
Assignee:
KURITA MASATAKE (JP)
NISHINO SATOSHI (JP)
NISHINO SATOSHI (JP)
International Classes:
A61K31/15; A61K45/00; A61P25/28
Other References:
AKIO SASHO ET AL.: "Chihosei Koreisha no BPSD (Mondai Kodo) ni Taisuru SSRI Luvox no Shiyo Keiken (the 2nd report)", POINTS OF LECTURE, CONGRESS OF THE JAPAN PHARMACEUTICAL ASSOCIATION, vol. 37, 2004, pages 174
KURITA,M. ET AL.: "Effects of fluvoxamine on behavioral and psychological symptoms of dementia in Alzheimer's disease: a report of three cases", FUKUSHIMA JOURNAL OF MEDICAL SCIENCE, vol. 52, no. 2, 2006, pages 143 - 148, XP055162432
MASATAKE KURITA ET AL.: "Alzheimer-gata Chiho no Kodo Shinrigakuteki Shoko (BPSD) ni Taishi fluvoxamine to quetiapine no Heiyo Ryoho ga Soko shita Ichirei", SEISHINKA CHIRYOGAKU, vol. 19, no. 12, 2004, pages 1479 - 1484
MANABU IKEDA: "Chihosho no Aratana Chiryo Senryaku Seishin Shojo to Kodo Ijo no Chiryo", CLINICAL NEUROLOGY, vol. 45, no. 11, 2005, pages 861 - 863
FUMIMARO TAKAKI ET AL., CHIRYOYAKU MANUAL 2007, IGAKU-SHOIN LTD., 2007, pages 212 - 213
KURITA,M. ET AL.: "Effects of fluvoxamine on behavioral and psychological symptoms of dementia in Alzheimer's disease: a report of three cases", FUKUSHIMA JOURNAL OF MEDICAL SCIENCE, vol. 52, no. 2, 2006, pages 143 - 148, XP055162432
MASATAKE KURITA ET AL.: "Alzheimer-gata Chiho no Kodo Shinrigakuteki Shoko (BPSD) ni Taishi fluvoxamine to quetiapine no Heiyo Ryoho ga Soko shita Ichirei", SEISHINKA CHIRYOGAKU, vol. 19, no. 12, 2004, pages 1479 - 1484
MANABU IKEDA: "Chihosho no Aratana Chiryo Senryaku Seishin Shojo to Kodo Ijo no Chiryo", CLINICAL NEUROLOGY, vol. 45, no. 11, 2005, pages 861 - 863
FUMIMARO TAKAKI ET AL., CHIRYOYAKU MANUAL 2007, IGAKU-SHOIN LTD., 2007, pages 212 - 213
Attorney, Agent or Firm:
FUKUMORI, Hisao (JP)
Hisao Fukumori (JP)
Hisao Fukumori (JP)
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