THERAPY VIA TARGETED DELIVERY OF NANOSCALE PARTICLES

Title:

THERAPY VIA TARGETED DELIVERY OF NANOSCALE PARTICLES

Document Type and Number:

WIPO Patent Application WO2004071370

Kind Code:

A3

Abstract:

Methods for treating cells, diseased tissue, pathogens, or other undesirable matter involve the administration of a bioprobe (energy susceptive materials that are attached to a target-specific ligand) to a patient's body, body part, tissue, or body fluid (such as blood, blood plasma, or blood serum). An energy source provides energy to the bioprobe so as to destroy, rupture, or inactivate the target. Various energy forms, such as AMF, microwave, acoustic, or a combination thereof, created via a variety of mechamisms can be used. The disclosed methods may be useful in the treatment of a variety of indications, including, but not limited to, cancer of any type, such as bone marrow, lung, vascular, neuro, colon, ovarian, breast and prostate cancer, AIDS, adverse angiogenesis, restenosis, amyloidosis, tuberculosis, obesity, malaria, and illnesses due to viruses, such as HIV.

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Inventors:

DAUM WOLFGANG (US)
ELLIS-BUSBY DIANE (US)
FOREMAN ALAN (US)
GOLDSTEIN ROBERT C (US)
GWOST DOUGLAS U (US)
SCHROEDER HANDY ERIK (US)
IVKOV ROBERT (US)
NEMKOV VALENTIN S (US)

Application Number:

PCT/US2004/003549

Publication Date:

February 02, 2006

Filing Date:

February 06, 2004

Export Citation:

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Assignee:

TRITON BIOSYSTEMS INC (US)
DAUM WOLFGANG (US)
ELLIS-BUSBY DIANE (US)
FOREMAN ALAN (US)
GOLDSTEIN ROBERT C (US)
GWOST DOUGLAS U (US)
SCHROEDER HANDY ERIK (US)
IVKOV ROBERT (US)
NEMKOV VALENTIN S (US)

International Classes:

A61N2/02; A61N2/00; A61N5/02; (IPC1-7): A61K39/395

Foreign References:

US6165440A	2000-12-26
US20020192221A1	2002-12-19
US4622952A	1986-11-18
US5688486A	1997-11-18

Other References:

GOVERNATORE DEL M ET AL: "Experimental photoimmunotherapy of hepatic metastases of colorectal cancer with a 17.1A chlorin immunoconjugate.", CANCER RES., vol. 60, 1 August 2000 (2000-08-01), pages 4200 - 4205, XP001028399

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