THERMAL EXPANSION-INDUCED FLUID CONTROL FOR MICROFLUIDIC DEVICES

Title:

THERMAL EXPANSION-INDUCED FLUID CONTROL FOR MICROFLUIDIC DEVICES

Document Type and Number:

WIPO Patent Application WO1999039120

Kind Code:

B1

Abstract:

A new method is proposed for the precise manipulation of picoliter-nanoliter volumes in microfluidic chips. The technique relies on the thermal expansion of fluids whereby fluid pressure and flow is easily manipulated through control of the fluid temperature. Heat can be efficiently applied in a sample manner using a light/infrared source (30) (e.g., a halogen lamp) which selectively heats the fluid (36) in the chip device through absorption of the optical energy in the visible-infrared (VIS/IR) portion of the electromagnetic spectrum. Several applications for fluid control and manipulation on microfluidic chips are proposed using the VIS/IR-induced fluid pumping mechanism, including valving.

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Inventors:

LANDERS JAMES P
HUHMER ANDREAS

Application Number:

PCT/US1999/001831

Publication Date:

September 16, 1999

Filing Date:

January 28, 1999

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Assignee:

UNIV PITTSBURGH (US)

International Classes:

B01L3/00; F16K13/10; (IPC1-7): F16K13/10; B01L3/00; C12Q1/68

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