THIAZOLE DERIVATIVE - OTSUKA PHARMA CO LTD

Title:

THIAZOLE DERIVATIVE

Document Type and Number:

WIPO Patent Application WO/1993/024472

Kind Code:

A1

Abstract:

A thiazole derivative which is excellent in an active oxygen inhibitory effect, represented by general formula (I), wherein R1 represents phenyl which may be substituted by 1 to 3 lower alkoxy groups, and R2 represents an optionally substituted pyridylcarbonyl group, a 5- to 15-membered mono-, di- or tricyclic heterocyclic group bearing 1 to 3 nitrogen, oxygen or sulfur atoms, or a substituted phenyl group.

Inventors:

CHIHIRO MASATOSHI (JP)
KOMATSU HAJIME (JP)
TOMINAGA MICHIAKI (JP)
YABUUCHI YOICHI (JP)

Application Number:

PCT/JP1993/000700

Publication Date:

December 09, 1993

Filing Date:

May 26, 1993

Export Citation:

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Assignee:

OTSUKA PHARMA CO LTD (JP)
CHIHIRO MASATOSHI (JP)
KOMATSU HAJIME (JP)
TOMINAGA MICHIAKI (JP)
YABUUCHI YOICHI (JP)

International Classes:

C07D277/22; C07D277/24; C07D277/26; C07D277/28; C07D277/30; C07D417/04; C07D417/06; C07D417/10; C07D417/12; C07D417/14; C07D498/04; C07F7/18; (IPC1-7): C07D277/22; A61K31/425; A61K31/44; C07D417/04; C07D417/06; C07D417/14; C07D498/04

Foreign References:

EP0310370A1	1989-04-05
EP0167973A1	1986-01-15
DE3026054A1	1981-02-05
EP0037710A1	1981-10-14
JPS61167685A	1986-07-29
EP0234729A2	1987-09-02
JPS55133366A	1980-10-17

Other References: