Title:
A THREE-DIMENSIONAL TISSUE SCAFFOLD WITH STEM CELL ATTRACTING ELEMENT AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/197491
Kind Code:
A1
Abstract:
Provided is a three dimensional tissue scaffold comprising a stem cell attracting element associated with a matrix, and fusion protein of stem cell attracting factor and collagen-binding domain, and methods of uses thereof.
Inventors:
DAI JIANWU (CN)
SUN JIE (CN)
CHEN BING (CN)
XIAO ZHIFENG (CN)
SUN JIE (CN)
CHEN BING (CN)
XIAO ZHIFENG (CN)
Application Number:
PCT/CN2015/091190
Publication Date:
December 15, 2016
Filing Date:
September 30, 2015
Export Citation:
Assignee:
INST GENETICS & DEV BIOLOG CAS (CN)
International Classes:
A61L27/54; A61K38/08
Domestic Patent References:
| WO2010048418A1 | 2010-04-29 |
Foreign References:
| CN104001212A | 2014-08-27 |
Other References:
HAN, QIANQIAN ET AL.: "Functional Collagen Biomaterials and Tissue Regeneration", CHINA MEDICAL DEVICE INFORMATION, 31 December 2012 (2012-12-31), pages 1 - 6
LIN, HANG ET AL.: "The effect of collagen-targeting platelet-derived growth factor on cellularization and vascularization of collagen scaffolds", CHINA MEDICAL DEVICE INFORMATION, vol. 27, 9 August 2006 (2006-08-09), pages 5708 - 5714, XP027951129
THEVENOT, P. T. ET AL.: "The effect of incorporation of SDF-la into PLGA scaffolds on stem cell recruitment and the inflammatory response", BIOMATERIALS, vol. 31, 24 February 2010 (2010-02-24), pages 3997 - 4008, XP026947574
LI, XIAORAN ET AL.: "Electrospun Collagen Fibers with Spatial Patterning of SDF1alpha for the Guidance of Neural Stem Cells", ADV. HEALTHCARE MATER., vol. 4, 29 June 2015 (2015-06-29), pages 1869 - 1876, XP055337182
LIN, HANG ET AL.: "The effect of collagen-targeting platelet-derived growth factor on cellularization and vascularization of collagen scaffolds", CHINA MEDICAL DEVICE INFORMATION, vol. 27, 9 August 2006 (2006-08-09), pages 5708 - 5714, XP027951129
THEVENOT, P. T. ET AL.: "The effect of incorporation of SDF-la into PLGA scaffolds on stem cell recruitment and the inflammatory response", BIOMATERIALS, vol. 31, 24 February 2010 (2010-02-24), pages 3997 - 4008, XP026947574
LI, XIAORAN ET AL.: "Electrospun Collagen Fibers with Spatial Patterning of SDF1alpha for the Guidance of Neural Stem Cells", ADV. HEALTHCARE MATER., vol. 4, 29 June 2015 (2015-06-29), pages 1869 - 1876, XP055337182
Attorney, Agent or Firm:
JUN HE LAW OFFICES (China Resources Building 8 Jianguomenbei Avenue, Beijing 5, CN)
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