Title:
TICK-ASSOCIATED VIRUS SEQUENCES AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/022958
Kind Code:
A3
Abstract:
The invention is directed to isolated tick-associated viruses and isolated nucleic acids sequences and polypeptides thereof. The invention also relates to antibodies against antigens from tick- associated viruses. The invention also relates to iRNAs which target nucleic acid sequences of the tick-associated virus. The invention is related to methods for detecting the presence or absence of tick-associated viruses in an animal. The invention is also related to immunogenic compositions for inducing an immune response against tick-associated viruses in an animal.
Inventors:
LIPKIN W IAN (US)
TOKARZ RAFAL (US)
TOKARZ RAFAL (US)
Application Number:
PCT/US2015/044284
Publication Date:
March 31, 2016
Filing Date:
August 07, 2015
Export Citation:
Assignee:
UNIV COLUMBIA (US)
International Classes:
C12N15/40
Domestic Patent References:
| WO2007130519A2 | 2007-11-15 | |||
| WO2007130519A2 | 2007-11-15 | |||
| WO2007130519A2 | 2007-11-15 | |||
| WO2014006226A1 | 2014-01-09 |
Foreign References:
| US20120076821A1 | 2012-03-29 | |||
| US20030165539A1 | 2003-09-04 |
Other References:
TOKARZ ET AL.: "Virome Analysis of Amblyomma american um, Dermacentor variabilis, and Ixodes scapularis Ticks Reveals Novel Highly Divergent Vertebrate and Invertebrate Viruses", JOURNAL OF VIROLOGY, vol. 88, no. 19, 23 July 2014 (2014-07-23), pages 11480 - 11492
DATABASE GenBank [o] 24 July 2014 (2014-07-24), "Powassan virus isolate LI-1 polyprotein gene", Database accession no. KJ746872
KUNO ET AL.: "Genomic sequencing of deer tick virus and phylogeny of powassan-related viruses of North America", AM. J. TROP. HYG., vol. 65, no. 5, 1 November 2001 (2001-11-01), pages 671 - 676, XP002982318
MANDL ET AL.: "Complete Genomic Sequence of Powassan Virus: Evaluation of Genetic Elements in Tick-Borne Versus Mosquito-Borne Flaviviruses", VIROLOGY, vol. 194, 1993, pages 173 - 184, XP025635728, DOI: doi:10.1006/viro.1993.1247
DATABASE GenBank [o] 24 July 2014 (2014-07-24), "Powassan virus isolate LI-1 polyprotein gene", Database accession no. KJ746872
KUNO ET AL.: "Genomic sequencing of deer tick virus and phylogeny of powassan-related viruses of North America", AM. J. TROP. HYG., vol. 65, no. 5, 1 November 2001 (2001-11-01), pages 671 - 676, XP002982318
MANDL ET AL.: "Complete Genomic Sequence of Powassan Virus: Evaluation of Genetic Elements in Tick-Borne Versus Mosquito-Borne Flaviviruses", VIROLOGY, vol. 194, 1993, pages 173 - 184, XP025635728, DOI: doi:10.1006/viro.1993.1247
Attorney, Agent or Firm:
CARNEY, Bonnie Kramer et al. (One Barker AvenueFifth Floo, White Plains NY, US)
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