Title:
TIGHT JUNCTION MITIGATOR, DRUG ABSORPTION AUXILIARY COMPRISING SAME, AND MEDICINAL COMPOSITION COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2016/190310
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a tight junction mitigator.
To solve the problem, provided is a tight junction mitigator that comprises at least one of the compounds represented by formulae (33-1), (33-9), (34-1), (34-2), (34-6) and (36-1).
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Inventors:
HIROAKI HIDEKAZU (JP)
TENNO TAKESHI (JP)
NODA SYOUTA (JP)
TENNO TAKESHI (JP)
NODA SYOUTA (JP)
Application Number:
PCT/JP2016/065324
Publication Date:
December 01, 2016
Filing Date:
May 24, 2016
Export Citation:
Assignee:
NAT UNIV CORP NAGOYA UNIV (JP)
International Classes:
A61K47/16; A61K47/22; A61K31/196; A61K31/341; A61K31/381; A61P43/00
Domestic Patent References:
| WO2005115374A1 | 2005-12-08 | |||
| WO2009015382A2 | 2009-01-29 | |||
| WO2007026516A1 | 2007-03-08 | |||
| WO2016013557A1 | 2016-01-28 |
Foreign References:
| JP2001527572A | 2001-12-25 | |||
| JP2010248094A | 2010-11-04 |
Other References:
WILLIAMS,J.R. ET AL.: "Unique Ligand Selectivity of the GPR92/LPA5 Lysophosphatidate Receptor Indicates Role in Human Platelet Activation", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 284, no. 25, 2009, pages 17304 - 17319, XP055332988
WU,S. ET AL.: "In Silico Screening for PTPN22 Inhibitors: Active Hits from an Inactive Phosphatase Conformation", CHEMMEDCHEM, vol. 4, 2009, pages 440 - 444, XP055332991
WU,S. ET AL.: "In Silico Screening for PTPN22 Inhibitors: Active Hits from an Inactive Phosphatase Conformation", CHEMMEDCHEM, vol. 4, 2009, pages 440 - 444, XP055332991
Attorney, Agent or Firm:
MATSUMOTO SEIJI (JP)
Seiji Matsumoto (JP)
Seiji Matsumoto (JP)
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