Title:
TISSUE ABLATION BY RAPID AND SUSTAINED ALTERATION IN MEMBRANE POTENTIAL
Document Type and Number:
WIPO Patent Application WO/2016/130385
Kind Code:
A3
Abstract:
A method for the ablation of undesirable tissue, such as cells of a cancerous or non-cancerous tumor, infected tissue, adipose tissue, wound, etc., comprising the injection of at least one ion channel or ion pump blocker into said undesirable tissue then applying a low voltage electrical current into said undesirable tissue to trigger a rapid and sustained change in membrane potential (Vm) of the targeted cells, causing said undesirable tissue to die by a process of programmed cell death (apoptosis) followed by immune system action on any surviving cells in the undesirable tissue. Alternatively, depending on the tissue type, a mechanical vibration or an osmotic force may be used instead of a low voltage electrical current.
Inventors:
EKEMA GEORGE MBELLA (US)
HEITZER MARJET DANTEEL (US)
HEITZER MARJET DANTEEL (US)
Application Number:
PCT/US2016/016464
Publication Date:
January 05, 2017
Filing Date:
February 03, 2016
Export Citation:
Assignee:
EKEMA GEORGE MBELLA (US)
HEITZER MARJET DANTEEL (US)
HEITZER MARJET DANTEEL (US)
International Classes:
A61N1/05; A61B18/12; A61N1/04
Domestic Patent References:
| WO2015021113A1 | 2015-02-12 |
Foreign References:
| US20070118107A1 | 2007-05-24 | |||
| US20150005767A1 | 2015-01-01 | |||
| US20120277741A1 | 2012-11-01 | |||
| US5468223A | 1995-11-21 | |||
| US20140039489A1 | 2014-02-06 |
Attorney, Agent or Firm:
EKEMA, George, Mbella (US)
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