Title:
TISSUE-DERIVED EXTRACELLULAR MATRIX DERIVATIVE MODIFIED WITH ACRYL GROUP AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/211517
Kind Code:
A1
Abstract:
The present invention relates to a tissue-derived extracellular matrix derivative modified with an acryl group and a use thereof. A composition for a hydrogel and a hydrogel prepared therefrom of the present invention can simulate fibrosis patterns of various tissues according to the degree of modification or crosslinking.
Inventors:
CHO SEUNG WOO (KR)
AN SOO HWAN (KR)
KIM SU KYEOM (KR)
KIM YU HEUN (KR)
AN SOO HWAN (KR)
KIM SU KYEOM (KR)
KIM YU HEUN (KR)
Application Number:
PCT/KR2022/004584
Publication Date:
October 06, 2022
Filing Date:
March 31, 2022
Export Citation:
Assignee:
UNIV YONSEI IACF (KR)
International Classes:
C12N11/087; C12N5/00; C12N5/071; C12N11/04
Foreign References:
| KR20190023002A | 2019-03-07 |
Other References:
PARTHIBAN S. PRAKASH, ATHIRASALA AVATHAMSA, TAHAYERI ANTHONY, ABDELMONIEM REYAN, GEORGE ANNE, BERTASSONI LUIZ E.: "BoneMA – Synthesis and Characterization of a Methacrylated Bone-derived Hydrogel for Bioprinting of Vascularized Tissues", BIORXIV, 4 March 2020 (2020-03-04), XP055973247, Retrieved from the Internet [retrieved on 20221020], DOI: 10.1101/2020.03.02.974063
KIM WONJIN; LEE HYEONGJIN; LEE JIUN; ATALA ANTHONY; YOO JAMES J.; LEE SANG JIN; KIM GEUN HYUNG: "Efficient myotube formation in 3D bioprinted tissue construct by biochemical and topographical cues", BIOMATERIALS, ELSEVIER, AMSTERDAM, NL, vol. 230, 19 November 2019 (2019-11-19), AMSTERDAM, NL , XP085965797, ISSN: 0142-9612, DOI: 10.1016/j.biomaterials.2019.119632
VISSCHER DAFYDD O.; LEE HYEONGJIN; VAN ZUIJLEN PAUL P.M.; HELDER MARCO N.; ATALA ANTHONY; YOO JAMES J.; LEE SANG JIN: "A photo-crosslinkable cartilage-derived extracellular matrix bioink for auricular cartilage tissue engineering", ACTA BIOMATERIALIA, ELSEVIER, AMSTERDAM, NL, vol. 121, 21 November 2020 (2020-11-21), AMSTERDAM, NL, pages 193 - 203, XP086472113, ISSN: 1742-7061, DOI: 10.1016/j.actbio.2020.11.029
LEE, BAEHUN: "Photocurable Protein-based Hydrogel", BRIC VIEW. TREND REPORT, WENZHOU INSTITUTE OF BIOMATERIALS AND ENGINEERING, WENZHOU MEDICAL UNIVERSITY, KR, vol. 2017-T35, 28 September 2017 (2017-09-28), KR, pages 1 - 18, XP009540169
KIM WONJIN; LEE HYEONGJIN; LEE JIUN; ATALA ANTHONY; YOO JAMES J.; LEE SANG JIN; KIM GEUN HYUNG: "Efficient myotube formation in 3D bioprinted tissue construct by biochemical and topographical cues", BIOMATERIALS, ELSEVIER, AMSTERDAM, NL, vol. 230, 19 November 2019 (2019-11-19), AMSTERDAM, NL , XP085965797, ISSN: 0142-9612, DOI: 10.1016/j.biomaterials.2019.119632
VISSCHER DAFYDD O.; LEE HYEONGJIN; VAN ZUIJLEN PAUL P.M.; HELDER MARCO N.; ATALA ANTHONY; YOO JAMES J.; LEE SANG JIN: "A photo-crosslinkable cartilage-derived extracellular matrix bioink for auricular cartilage tissue engineering", ACTA BIOMATERIALIA, ELSEVIER, AMSTERDAM, NL, vol. 121, 21 November 2020 (2020-11-21), AMSTERDAM, NL, pages 193 - 203, XP086472113, ISSN: 1742-7061, DOI: 10.1016/j.actbio.2020.11.029
LEE, BAEHUN: "Photocurable Protein-based Hydrogel", BRIC VIEW. TREND REPORT, WENZHOU INSTITUTE OF BIOMATERIALS AND ENGINEERING, WENZHOU MEDICAL UNIVERSITY, KR, vol. 2017-T35, 28 September 2017 (2017-09-28), KR, pages 1 - 18, XP009540169
Attorney, Agent or Firm:
PCR INTELLECTUAL PROPERTY LAW FIRM (KR)
Download PDF: