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Title:
TISSUE-ENGINEERED VASCULAR GRAFT AND ITS FABRICATION APPROACH
Document Type and Number:
WIPO Patent Application WO/2013/151463
Kind Code:
A3
Abstract:
Tissue-engineered vascular graft is designed to be used in cardiovascular surgeries, especially in coronary artery bypass grafting and peripheral vessels reconstruction procedures. Two-phase electrospinning technique was employed to fabricate a biodegradable polymer graft composed of the porous tubular scaffold supplemented by biologically active molecules, incorporated directly into the matrix walls in order to promote regeneration process of the patient's own vessel wall.

Inventors:
BARBARASH LEONID SEMENOVICH (RU)
ELGUDIN JACOB LVOVICH (US)
SEVOSTYANOVA VICTORIA VLADIMIROVNA (RU)
GOLOVKIN ALEXEY SERGEYEVICH (RU)
Application Number:
PCT/RU2013/000250
Publication Date:
November 28, 2013
Filing Date:
March 27, 2013
Export Citation:
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Assignee:
FEDERALNOE G BJUDZHETNOE UCHREZHDENIE NIINST KOMPLEKSNYKH SERDECHNO SOSUDISTYKH ZABOLEVANY SIB OTDEL (RU)
International Classes:
A61F2/06; A61L27/44; A61L27/54; A61L27/58; A61L33/06
Domestic Patent References:
WO2011066401A12011-06-03
Foreign References:
US20100221304A12010-09-02
US20060100717A12006-05-11
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