TISSUE FIBROSIS BIOMARKER

WIPO Patent Application WO/2018/168769

A1

The purpose of the present invention is to provide a biomarker for diseases associated with tissue fibrosis, and a method for using the biomarker. The present invention involves an extracellular-vesicles protein group (A) which is in a body fluid collected from a subject.

WO/2017/039107	NEW XYLENE-BASED AMPHIPATHIC COMPOUND AND USE THEREOF
WO/1989/011489	IMMUNOGENIC HUMAN INTERLEUKIN-3 PEPTIDE AND MONOCLONAL ANTIBODIES THERETO
WO/2003/089935	THE METHOD FOR MEASURING THE AMOUNT OF $g(b)iG-H3 PROTEIN AND DIAGNOSTIC KIT USING THE SAME

TAKEDA YOSHITO (JP)
KUMANOGOH ATSUSHI (JP)
MATSUKI TAKANORI (JP)
UEDA KOJI (JP)

PCT/JP2018/009503

September 20, 2018

March 12, 2018

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UNIV OSAKA (JP)
JAPANESE FOUND FOR CANCER RES (JP)

G01N33/68; A61K45/00; A61P11/00; G01N33/15; G01N33/50

WO2014006230A1	2014-01-09
WO2003072134A1	2003-09-04

US20100184046A1

2010-07-22

UEDA, K. ET AL.: "ANTIBODY-COUFLED MONOLITHIC SILICA MICROTIPS FOR HIGHTHROUGHPUT MOLECULAR PROFILING OF CIRCULATING EXOSOMES", SCIENTIFIC REPORTS, vol. 4, 29 August 2014 (2014-08-29), pages 1 - 9, XP055545745
KADOTA, T. ET AL.: "EXTRACELLULAR VESICLES IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 17, no. 11, 27 October 2016 (2016-10-27), XP055545753
YAMADA, MITSUHIRO: "Biomarker using exosome for vascular inflammation", VASCULAR BIOLOGY & MEDICINE, vol. 16, no. 2, June 2015 (2015-06-01), pages 61 - 68

SAEGUSA & PARTNERS (JP)

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