Title:
TISSUE SPECIFIC EXPRESSION OF EXOGENOUS PROTEINS IN TRANSGENIC CHICKENS
Document Type and Number:
WIPO Patent Application WO2004015123
Kind Code:
A8
Abstract:
Transgenes encoding exogenous proteins are stably integrated into embryonic stem cells and are present in the somatic tissue of transgenic or chimeric birds. The transgenes encode exogenous proteins and are expressed in any of endodermal, ectodermal, mesodermal, or extra embryonic tissue. Tissue specificity is provided by selecting the content of the transgene accordingly. Transgenic birds whose genome is comprised of trangene derived exogenous DNA express exogenous proteins with tissue specificity, and specifically express exogenous proteins in the tubular gland cells of the oviduct to concentrate exogenous proteins in egg white.
Inventors:
ZHU LEI
WINTERS-DIGIACINTO PEGGY
ETCHES ROBERT
WINTERS-DIGIACINTO PEGGY
ETCHES ROBERT
Application Number:
PCT/US2003/025270
Publication Date:
March 17, 2005
Filing Date:
August 11, 2003
Export Citation:
Assignee:
ORIGEN THERAPEUTICS (US)
International Classes:
A01K67/027; C12N15/09; C12N15/85; (IPC1-7): C12P21/00; C12P21/06; A01K67/00; A01K67/027; C12N5/00; C12N15/00; C12N15/63
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