TISSUE-SPECIFIC EXTRACELLULAR MATRIX WITH OR WITHOUT TISSUE PROTEIN COMPONENTS FOR CELL CULTURE

Title:

TISSUE-SPECIFIC EXTRACELLULAR MATRIX WITH OR WITHOUT TISSUE PROTEIN COMPONENTS FOR CELL CULTURE

Document Type and Number:

WIPO Patent Application WO/2012/064606

Kind Code:

A3

Abstract:

The present invention relates to compositions and methods for mimicking an in vivo environment for culturing cells in vitro. The in vivo mimicking environment is based on the generation of a tissue-specific extracellular matrix wherein the matrix provides a substrate for which the cultured cell originated from. The tissue-specific extracellular matrix can further comprise a component of a whole tissue-specific homogenate.

Inventors:

ZHANG YUANYUAN (US)
SOKER SHAY (US)
ATALA ANTHONY (US)

Application Number:

PCT/US2011/059349

Publication Date:

July 12, 2012

Filing Date:

November 04, 2011

Export Citation:

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Assignee:

UNIV WAKE FOREST HEALTH SCIENCES (US)
ZHANG YUANYUAN (US)
SOKER SHAY (US)
ATALA ANTHONY (US)

International Classes:

C12M3/00

Foreign References:

US20100093077A1	2010-04-15
US20070269476A1	2007-11-22
US20080194010A1	2008-08-14

Attorney, Agent or Firm:

NGUYEN, Quang, D. et al. (LLP300 Four Falls Corporate Center, Suite 710,300 Conshohocken State Roa, West Conshohocken PA, US)

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