TOPICAL BRIMONIDINE TARTRATE OPHTHALMIC SOLUTION

Title:

TOPICAL BRIMONIDINE TARTRATE OPHTHALMIC SOLUTION

Document Type and Number:

WIPO Patent Application WO/2015/097600

Kind Code:

A3

Abstract:

The present invention provides an aqueous ophthalmic composition comprising an alpha-2 adrenergic receptor agonist and a non-ionic cellulosic polymer, the solution having a pH less than 6.5. The present invention also provides an aqueous ophthalmic composition comprising an alpha-2 adrenergic receptor agonist and a benzododecinium halide. Also provided are methods of manufacture, use and method of reducing intraocular pressure in the patient in need thereof.

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Inventors:

SHAH MANDAR V (IN)
BAHRI DEEPAK (IN)

Application Number:

PCT/IB2014/067066

Publication Date:

October 29, 2015

Filing Date:

December 18, 2014

Export Citation:

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Assignee:

SENTISS PHARMA PRIVATE LTD (IN)

International Classes:

A61K9/08; A61K31/498; A61K47/18; A61K47/38; A61P27/02

Domestic Patent References:

WO2011027365A2

2011-03-10

Foreign References:

US20100203165A1	2010-08-12
US6627210B2	2003-09-30

Other References:

MEGHA BAROT ET AL: "Trends in Ophthalmic Preservatives: A Review", DRUG DELIVERY TECHNOLOGY, vol. 10, no. 6, 2010, pages 46 - 49, XP055182914, ISSN: 1537-2898

Attorney, Agent or Firm:

BHATTACHARYYA, Goutam et al. (Intellectual Property Attorneys109, Sector 4, Gurgaon National Capital Region 3, IN)

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