Title:
TOPICAL GEL FORMULATION COMPRISING ORGANOPHOSPHATE INSECTICIDE AND ITS PREPARATION THEREOF
Document Type and Number:
WIPO Patent Application WO2006017263
Kind Code:
A9
Abstract:
The present invention provides a topical gel pharmaceutical formulation of insecticide suitable for treating an ectoparasite in a mammal, comprising: a) about 0.1-10 % by weight of an insecticide; b) at least about 75 % by weight of an organic solvent selected from the group consisting of a lower alkyl alcohol, a ketone, a glycol and a mixture thereof, wherein the organic solvent contains at least about 40 % by weight of the lower alkyl alcohol; and c) at least one polymer selected from the group consisting of a cellulosic polymer, acrylates, methacrylates, and polyvinyl pyrrolidone. The present gel pharmaceutical formulation preferably contains malathion and optionally contains isopropyl myristate. The present invention further provides a process of preparing as well as a method of treating ectoparasites in a mammal using the same.
Inventors:
GOYAL SANDHYA (US)
KUNDUS SUBHAS (US)
MOROS DANIEL (US)
RUTMAN HOWARD (US)
YACOBI AVRAHAM (US)
KUNDUS SUBHAS (US)
MOROS DANIEL (US)
RUTMAN HOWARD (US)
YACOBI AVRAHAM (US)
Application Number:
PCT/US2005/024643
Publication Date:
June 01, 2006
Filing Date:
July 12, 2005
Export Citation:
Assignee:
TARO PHARMA IND (IL)
GOYAL SANDHYA (US)
KUNDUS SUBHAS (US)
MOROS DANIEL (US)
RUTMAN HOWARD (US)
YACOBI AVRAHAM (US)
GOYAL SANDHYA (US)
KUNDUS SUBHAS (US)
MOROS DANIEL (US)
RUTMAN HOWARD (US)
YACOBI AVRAHAM (US)
International Classes:
(IPC1-7): A01N25/04
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