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Patent Searching and Data


Title:
TOTAL SYNTHESIS OF TRIOXACARCIN DC-45-A2 AND PREPARATION OF TRIOXACARCIN ANALOGS
Document Type and Number:
WIPO Patent Application WO/2016/100833
Kind Code:
A3
Abstract:
In one aspect, the present invention provides novel derivatives of trioxacarin analogs of the formula (I) wherein the variables are as defined herein. The application also provides compositions, methods of treatment, and methods of synthesis thereof.

Inventors:
NICOLAOU KYRIACOS C (US)
CAI QUAN (US)
Application Number:
US2015/066703
Publication Date:
January 05, 2017
Filing Date:
December 18, 2015
Export Citation:
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Assignee:
UNIV RICE WILLIAM M (US)
International Classes:
C07H15/24; C07H15/26; C07H17/04
Foreign References:
US20130150314A12013-06-13
Other References:
SVENDA ET AL.: "A multiply convergent platform for the synthesis of trioxacarcins", PNAS, vol. 108, 2011, pages 6709 - 6714, XP055001184
See also references of EP 3233877A4
Attorney, Agent or Firm:
LONG, S., Reid (1120 S. Capital of Texas HighwayBuilding One, Suite 20, Austin TX, US)
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