Title:
TRANSCRIPTION REGULATORY SEQUENCE
Document Type and Number:
WIPO Patent Application WO/2004/111238
Kind Code:
A1
Abstract:
It is intended to construct a method of producing a useful protein with the use of the protein secretion system into urine by which purification, etc. can be easily performed and a high production efficiency and a favorable production cost can be achieved. Namely, a transcription regulatory sequence that comprises a nucleic acid molecule having a transcription regulatory activity acting in distal renal tubule cells in kidney (in particular such a transcription regulatory sequence originating in a feline aged 3 months or more belonging to Felis catus, Felinae such as a transcription regulatory sequence of cauxin gene); an expression vehicle or a transformed cell containing the above transcription regulatory sequence; and a method of expressing a foreign gene and producing a foreign protein using the same.
Inventors:
YAMASHITA TETSURO (JP)
MIYAZAKI MASAO (JP)
MIYAZAKI MASAO (JP)
Application Number:
PCT/JP2004/007927
Publication Date:
December 23, 2004
Filing Date:
June 07, 2004
Export Citation:
Assignee:
TOHOKU TECHNO ARCH CO LTD (JP)
YAMASHITA TETSURO (JP)
MIYAZAKI MASAO (JP)
YAMASHITA TETSURO (JP)
MIYAZAKI MASAO (JP)
International Classes:
A61P13/12; C12N9/18; C12N15/12; A61K48/00; (IPC1-7): C12N15/12; A01K67/027; A61K38/00; A61K48/00; A61P13/12; C12N5/10
Other References:
MIYAZAKI M. ET AL: "Molecular cloning and characterization of a novel carboxylesterase-like protein that is physiologically present at high concentrations in the urine of domestic cats (felis catus)", BIOCHEM. JOURNAL, vol. 370, 2003, pages 101 - 110, XP002981087
Attorney, Agent or Firm:
Abe, Masahiro (14-1 Maebara-nishi 2-chome, Funabashi-sh, Chiba 25, JP)
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