Title:
TRANSFERRIN RECEPTOR APTAMERS AND APTAMER-TARGETED DELIVERY
Document Type and Number:
WIPO Patent Application WO/2013/163303
Kind Code:
A3
Abstract:
Aptamers targeted to a human transferrin receptor which do not compete with transferrin for binding are provided. Compositions and methods for aptamer-targeted liposomal drug delivery are also provided.
Inventors:
LEVY MATTHEW (US)
MAIER KEITH EVERETT (US)
WILNER SAMANTHA E (US)
MAIER KEITH EVERETT (US)
WILNER SAMANTHA E (US)
Application Number:
PCT/US2013/038006
Publication Date:
January 30, 2014
Filing Date:
April 24, 2013
Export Citation:
Assignee:
EINSTEIN COLL MED (US)
International Classes:
C07H21/02; A61K48/00; C40B50/06
Domestic Patent References:
| WO2011142798A2 | 2011-11-17 |
Foreign References:
| US20100261781A1 | 2010-10-14 | |||
| US20080008996A1 | 2008-01-10 | |||
| US6812339B1 | 2004-11-02 |
Other References:
WILLIS, M ET AL.: "Liposome-Anchored Vascular Endothelial Growth Factor Aptamers.", BIOCONJUGATE CHEMISTRY., vol. 9, no. 5, 10 July 1998 (1998-07-10), pages 573 - 582, XP000778000, DOI: doi:10.1021/bc980002x
KANG, H ET AL.: "A Liposome-Based Nanostructure For Aptamer Directed Delivery.", CHEMICAL COMMUNICATION, vol. 46, no. 2, 23 November 2009 (2009-11-23), pages 249 - 251
KANG, H ET AL.: "A Liposome-Based Nanostructure For Aptamer Directed Delivery.", CHEMICAL COMMUNICATION, vol. 46, no. 2, 23 November 2009 (2009-11-23), pages 249 - 251
Attorney, Agent or Firm:
MILLER, Alan D. et al. (Rothstein & Ebenstein LLP90 Park Avenu, New York NY, US)
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