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Title:
TRANSFORMANT AND PROCESS FOR PRODUCTION THEREOF, AND PROCESS FOR PRODUCTION OF LACTIC ACID
Document Type and Number:
WIPO Patent Application WO/2015/076393
Kind Code:
A1
Abstract:
 The present invention relates to a transformant having Schizosaccharomyces pombe as the host, the transformant incorporating a D-lactate dehydrogenase gene from bacteria of the genus Pediococcus and a D-lactate dehydrogenase gene from bacteria of the genus Lactobacillus and deleting or inactivating some of the genes among a gene group encoding pyruvate decarboxylase in the Schizosaccharomyces pombe host.

Inventors:
HARA FUTOSHI (JP)
KIMURA SHUICHIRO (JP)
HAGIYA YUICHIRO (JP)
TANAKA TAKAYUKI (JP)
Application Number:
PCT/JP2014/080982
Publication Date:
May 28, 2015
Filing Date:
November 21, 2014
Export Citation:
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Assignee:
ASAHI GLASS CO LTD (JP)
International Classes:
C12N1/19; C12P7/56; C12N15/09
Domestic Patent References:
WO2011021629A12011-02-24
WO2011021629A12011-02-24
WO2007063919A12007-06-07
WO2002101038A12002-12-19
WO2007015470A12007-02-08
WO1995009914A11995-04-13
WO1999023223A11999-05-14
WO2007026617A12007-03-08
WO1996023890A11996-08-08
Foreign References:
JP2005102625A2005-04-21
JP2007512018A2005-05-04
JPH0515380A1993-01-26
JPH10234375A1998-09-08
JP2000262284A2000-09-26
JP2005198612A2005-07-28
JPH07163373A1995-06-27
JPH10234375A1998-09-08
Other References:
WANMENG M. ET AL.: "Characterization of d-lactate dehydrogenase from Pediococcus acidilactici that converts phenylpyruvic acid into phenyllactic acid", BIOTECHNOL.LETT., vol. 34, no. 5, 2012, pages 907 - 911, XP035053484
XIAOQIANG J. ET AL.: "D-lactic acid production by a genetically engineered strain Corynebacterium glutamicum", WORLD J.MICROBIOL. BIOTECHNOL., vol. 27, no. 9, 2011, pages 2117 - 2124, XP019937711
FUTOSHI HARA ET AL.: "Lactate production using Schizosaccharomyces pombe", DAI 61 KAI ABSTRACTS OF THE ANNUAL MEETING OF THE SOCIETY FOR BIOTECHNOLOGY, 2009, JAPAN, pages 190, XP008151367
SHOHEI OKINO ET AL.: "Coryneform Saikin o Mochiita D-Nyusan no Seisan", JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY, vol. 267, 2008, pages 3A26 P12, XP008183263
THE JOURNAL OF NUCLEIC ACIDS RES., vol. 34, 2006, pages E11
"Experimental Method of Yeast Molecular Genetics", 1996, GAKKAI SHUPPAN CENTER
THE JOURNAL OF PCR METHODS APPL., vol. 2, 1992, pages 28 - 33
THE JOURNAL OF YEAST, vol. 14, 1998, pages 943 - 951
NATHAN J. BOWEN ET AL.: "Retrotransposons and Their Recognition of pol II Promoters: A Comprehensive Survey of the Transposable Elements from the Complete Genome Sequence of Schizosaccharomyces pombe", GENOME RES., vol. 13, 2003, pages 1984 - 1997
THE JOURNAL OF NUCLEIC ACIDS RES, vol. 34, 2006, pages E11
BAHLER ET AL., THE JOURNAL OF YEAST, vol. 14, 1998, pages 943 - 951
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Attorney, Agent or Firm:
HAMADA Yuriko et al. (JP)
Yuriko Hamada (JP)
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