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Patent Searching and Data


Title:
TRANSFORMANT USED FOR LOSING WEIGHT AND REDUCING FAT, CONSTRUCTION METHOD FOR TRANSFORMANT, AND APPLICATION OF TRANSFORMANT
Document Type and Number:
WIPO Patent Application WO/2016/150392
Kind Code:
A1
Abstract:
Provided are a transformant used for losing weight and reducing fat, and a construction method for the transformant. The transformant is a recombinant lactococcus lactis obtained by replacing a lactococcus lactis thymidylate synthase gene with a codon optimised human oxyntomodulin gene via homologous recombination. Also provided is an application of the transformant in the preparation of a blood glucose-reducing drug, a fat-reducing drug and a food.

Inventors:
LIN YAN (CN)
XIANG RONG (CN)
ZHAO ALLANZIJIAN (CN)
LI FANGHONG (CN)
Application Number:
PCT/CN2016/077184
Publication Date:
September 29, 2016
Filing Date:
March 24, 2016
Export Citation:
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Assignee:
NANJING SINOGEN BIOTECH & PHARMACEUTICAL INC (CN)
International Classes:
C12N1/21; A61K38/26; A61K48/00; A61P3/04; A61P3/06; A61P3/10; C12N15/16; C12N15/90; C12R1/46
Foreign References:
CN101608172A2009-12-23
Other References:
LONG, RUOTING ET AL.: "Expression of bifidobacteria oxyntomodulin in bifidobacteria and effect of oxyntomodulin-transformed on the body weight of obese mice", JOURNAL OF SOUTHERN MEDICAL UNIVERSITY, vol. 29, no. 9, 30 September 2009 (2009-09-30), pages 1796 - 1798, XP055422564, ISSN: 1673-4252
LONG, RUOTING;: "Expression of oxyntomodulin (OXM) in bifidobacterium and the effect on food intake and bodyweight of fat mouse", CHINA DOCTORAL DISSERTATIONS FULL-TEXT DATABASE (BASIC SCIENCES, 15 December 2009 (2009-12-15), pages A006 - 41, XP009501442, ISSN: 1674-022X
Attorney, Agent or Firm:
NANJING SUGAO PATENT AND TRADEMARK FIRM (ORDINARY PARTNERSHIP) (CN)
南京苏高专利商标事务所(普通合伙) (CN)
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