Title:
TRANSFORMED CAENORHABDITIS ELEGANS AND METHOD FOR SCREENING FOR SUBSTANCES REGULATING GLUCOSE METABOLISM USING SAME
Document Type and Number:
WIPO Patent Application WO/2012/161538
Kind Code:
A2
Abstract:
The present invention relates to a method for preparing a transformed Caenorhabditis elegans (C. elegans) which reacts to glucose by exhibiting fluorescence, and to a method for screening for a candidate substance and for a novel gene capable of regulating glucose metabolism and metabolic diseases using the transformed Caenorhabditis elegans. The transformed Caenorhabditis elegans of the present invention is prepared such that changes in glucose may be easily observed on a real-time basis using a fluorescent microscope. The transformed Caenorhabditis elegans of the present invention enables substances for regulating glucose metabolism to be quickly and accurately discovered, and further, may be expected to significantly contribute to studies on a variety of incurable metabolism-related diseases such as obesity, diabetes, and the like.
Inventors:
LEE SEUNG JAE (KR)
LEE DONG YEOP (KR)
LEE DONG YEOP (KR)
Application Number:
PCT/KR2012/004133
Publication Date:
November 29, 2012
Filing Date:
May 24, 2012
Export Citation:
Assignee:
POSTECH ACAD IND FOUND (KR)
LEE SEUNG JAE (KR)
LEE DONG YEOP (KR)
LEE SEUNG JAE (KR)
LEE DONG YEOP (KR)
International Classes:
A01K67/027; C12N5/10; C12N15/62; C12N15/63; C12N15/85
Domestic Patent References:
| WO2002057440A2 | 2002-07-25 |
Foreign References:
| US20070274952A1 | 2007-11-29 |
Other References:
None
See also references of EP 2716155A4
See also references of EP 2716155A4
Attorney, Agent or Firm:
ERUUM PATENT LAW FIRM (KR)
특허법인 이룸 (KR)
특허법인 이룸 (KR)
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Claims: