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Title:
TRANSTHYRETIN ANTIBODIES AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2014/124334
Kind Code:
A3
Abstract:
The present invention provides compositions comprising anti-transthyretin antibodies. The compositions are particularly useful for diagnosis, prognosis and/or treatment of amyloid diseases or symptoms thereof.

Inventors:
JIANG XIN (US)
KELLY JEFFERY W (US)
CHAPMAN JUSTIN (US)
Application Number:
PCT/US2014/015421
Publication Date:
December 24, 2014
Filing Date:
February 07, 2014
Export Citation:
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Assignee:
MISFOLDING DIAGNOSTICS INC (US)
International Classes:
C07K16/18; A61K39/395; A61P25/00; G01N33/53
Domestic Patent References:
WO2010030203A12010-03-18
WO2011100396A22011-08-18
Foreign References:
JP2010195710A2010-09-09
Other References:
ANDO ET AL.: "Transthyretin-related familial amyloidotic polyneuropathy", ARCHIVES OF NEUROLOGY, vol. 62, no. 7, 2005, pages 1057 - 1062, XP008179756
UEDA ET AL.: "Clinicopathological features of senile systemic amyloidosis: an ante- and post-mortem study", MODERN PATHOLOGY, vol. 24, no. 12, 2011, pages 1533 - 1544, XP055262791
See also references of EP 2953970A4
Attorney, Agent or Firm:
HSU, Jennifer et al. (650 Page Mill RoadPalo Alto, CA, US)
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