Title:
TREATMENT OF CNS DISORDERS USING CNS TARGET MODULATORS
Document Type and Number:
WIPO Patent Application WO2005103041
Kind Code:
A3
Abstract:
The invention is directed to compositions and methods useful for treating Central Nervous System (CNS) disorders. Furthermore, the invention provides compositions and methods of treating sleep disorders. More specifically, the invention is directed to the compositions and use of derivatized, histamine antagonists for the treatment of sleep disorders.
Inventors:
EDGAR DALE M (US)
HANGAUER DAVID G (US)
LEIGHTON HARRY JEFFERSON (US)
MIGNOT EMMANUEL J M (US)
WHITE JAMES F (US)
SOLOMON MICHAEL (US)
SHIOSAKI KAZUMI (US)
HANGAUER DAVID G (US)
LEIGHTON HARRY JEFFERSON (US)
MIGNOT EMMANUEL J M (US)
WHITE JAMES F (US)
SOLOMON MICHAEL (US)
SHIOSAKI KAZUMI (US)
Application Number:
PCT/US2005/014186
Publication Date:
October 19, 2006
Filing Date:
April 25, 2005
Export Citation:
Assignee:
HYPNION INC (US)
EDGAR DALE M (US)
HANGAUER DAVID G (US)
LEIGHTON HARRY JEFFERSON (US)
MIGNOT EMMANUEL J M (US)
WHITE JAMES F (US)
SOLOMON MICHAEL (US)
SHIOSAKI KAZUMI (US)
EDGAR DALE M (US)
HANGAUER DAVID G (US)
LEIGHTON HARRY JEFFERSON (US)
MIGNOT EMMANUEL J M (US)
WHITE JAMES F (US)
SOLOMON MICHAEL (US)
SHIOSAKI KAZUMI (US)
International Classes:
A61P25/00; A61K31/445; A61K31/54; A61K31/553; A61K31/554; A61K47/48; C07D211/08; C07D211/14; C07D211/46; C07D211/70; C07D213/38; C07D213/55; C07D243/10; C07D243/38; C07D267/02; C07D273/06; C07D279/22; C07D281/16; C07D313/12; C07D401/06; C07D405/04; C07D405/14; C07D413/02; C07D417/04
Domestic Patent References:
| WO2003032912A2 | 2003-04-24 |
Other References:
IWASAKI ET AL.: "Amphoteric Drugs. I. Synthesis and Antiallergic Activity of [4-(Diphenylmethoxy)piperidino]-, [4-(Diphenylmethyl)piperazinyl]- and [4-(Diphenylmethylene)piperidino]alkanoic Acid Derivatives", CHEMICAL & PHARMACEUTICAL BULLETIN, vol. 42, no. 11, 1994, pages 2276 - 2284, XP002128280
See also references of EP 1742707A4
See also references of EP 1742707A4
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