Title:
TREATMENT AND DIAGNOSIS OF IMMUNE DISORDERS
Document Type and Number:
WIPO Patent Application WO/2011/008947
Kind Code:
A3
Abstract:
Disclosed are composition and methods for treating immune disorders. Also disclosed are diagnosis methods and prognosis methods.
Inventors:
ZHU ZHENGLUN (US)
GAO HONG (US)
GAO HONG (US)
Application Number:
PCT/US2010/042126
Publication Date:
July 21, 2011
Filing Date:
July 15, 2010
Export Citation:
Assignee:
ZHU ZHENGLUN (US)
GAO HONG (US)
GAO HONG (US)
International Classes:
C12N15/113; A61K31/7105; A61K48/00; A61P31/00; A61P37/00; C12Q1/68; G01N33/53
Domestic Patent References:
| WO2007051077A2 | 2007-05-03 |
Foreign References:
| US20070248535A1 | 2007-10-25 | |||
| US20040223952A1 | 2004-11-11 |
Other References:
M. SHULEWITZ ET AL: "Repressor roles for TCF-4 and Sfrp1 in Wnt signaling in breast cancer", ONCOGENE, vol. 25, no. 31, 2006, pages 4361 - 4369, XP002592812
DATABASE GENBANK 4 October 2006 (2006-10-04), "Homo sapiens VENT homeobox homolog (Xenopus laevis), mRNA (cDNA clone MGC:119911 IMAGE:40015553), complete cds", XP008150163, Database accession no. BC108916
ARCE L. ET AL: "Diversity of LEF/TCF action in development and disease", ONCOGENE, vol. 25, no. 57, 2006, pages 7492 - 7504, XP008150166
P. MAYE ET AL: "Multiple mechanisms for Wnt11-mediated repression of the canonical Wnt signaling pathway", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 279, no. 23, 2004, pages 24659 - 24665, XP008150170
FENG CONG ET AL: "Requirement for a nuclear function of beta-catenin in Wnt signaling", MOLECULAR AND CELLULAR BIOLOGY, vol. 23, no. 23, 2003, pages 8462 - 8470, XP008150167
DATABASE GENBANK 4 October 2006 (2006-10-04), "Homo sapiens VENT homeobox homolog (Xenopus laevis), mRNA (cDNA clone MGC:119911 IMAGE:40015553), complete cds", XP008150163, Database accession no. BC108916
ARCE L. ET AL: "Diversity of LEF/TCF action in development and disease", ONCOGENE, vol. 25, no. 57, 2006, pages 7492 - 7504, XP008150166
P. MAYE ET AL: "Multiple mechanisms for Wnt11-mediated repression of the canonical Wnt signaling pathway", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 279, no. 23, 2004, pages 24659 - 24665, XP008150170
FENG CONG ET AL: "Requirement for a nuclear function of beta-catenin in Wnt signaling", MOLECULAR AND CELLULAR BIOLOGY, vol. 23, no. 23, 2003, pages 8462 - 8470, XP008150167
Attorney, Agent or Firm:
TSAO, Y. Rocky et al. (10 Fawcett StreetCambridge, Massachusetts, US)
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