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Title:
TREATMENT OF MALE SEXUAL DYSFUNCTION
Document Type and Number:
WIPO Patent Application WO2002003995
Kind Code:
A3
Abstract:
The present invention relates to the use of neutral endopeptidase inhibitors (NEPi) and a combination of NEPi and phosphodiesterase type (PDE5) inhibitor for the treatment of male sexual dysfunction, in particular MED.

Inventors:
NAYLOR ALASDAIR MARK (GB)
VAN DER GRAAF PIETER HADEWIJN (GB)
WAYMAN CHRISTOPHER PETER (GB)
Application Number:
PCT/IB2001/001187
Publication Date:
April 18, 2002
Filing Date:
July 02, 2001
Export Citation:
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Assignee:
PFIZER LTD (GB)
PFIZER (US)
NAYLOR ALASDAIR MARK (GB)
GRAAF PIETER HADEWIJN V D (GB)
WAYMAN CHRISTOPHER PETER (GB)
International Classes:
A61K31/00; A61K31/165; A61K31/17; A61K31/18; A61K31/19; A61K31/192; A61K31/196; A61K31/395; A61K31/40; C07D285/135; A61K31/4015; A61K31/433; A61K31/4412; A61K31/454; A61K45/00; A61K45/06; A61P15/10; A61P43/00; C07C233/58; C07C233/60; C07C235/40; C07C237/22; C07C237/24; C07C275/52; C07C311/13; C07C311/18; C07C311/51; C07D207/14; C07D207/27; C07D209/14; C07D211/40; C07D213/64; C07D213/70; C07D213/75; C07D285/12; C07D307/81; C07D317/58; C07D207/26; (IPC1-7): A61K31/55; A61K31/401; A61K31/4166; A61K31/41; A61K31/421; A61K31/4365; A61K31/17; A61K31/16; A61P15/10
Domestic Patent References:
WO1999055723A11999-11-04
WO1991010644A11991-07-25
Other References:
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1991, NOUEL D ET AL: "INHIBITION OF APOMORPHINE-INDUCED YAWNING AND PENILE ERECTION BY NEUROTENSIN", XP002188344, Database accession no. PREV199192127654
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1994, AGMO ANDERS ET AL: "Enkephalinase inhibition facilitates sexual behavior in the male rat but does not produce conditioned place preference.", XP002188345, Database accession no. PREV199497237130
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