Title:
TREATMENT OF MIGRAINE BY THE ADMINISTRATION OF ALPHA-LIPOIC ACID OR DERIVATIVES THEREOF
Document Type and Number:
WIPO Patent Application WO2001015693
Kind Code:
A3
Abstract:
The invention relates to the use of racemic alpha -lipoic acid, or its enantiomers or pharmaceutically acceptable salts, amides, esters or thioesters thereof in reduced or oxidised form, as an active ingredient for the prevention or treatment of acute or chronic migraine.
Inventors:
SCHOENEN JEAN
ENGEL JUERGEN
WESSEL KLAUS
PEUKERT MANFRED
LOBISCH MICHAEL
BORBE HARALD
ENGEL JUERGEN
WESSEL KLAUS
PEUKERT MANFRED
LOBISCH MICHAEL
BORBE HARALD
Application Number:
PCT/EP2000/008315
Publication Date:
December 20, 2001
Filing Date:
August 26, 2000
Export Citation:
Assignee:
ASTA MEDICA AG (DE)
International Classes:
A61K31/385; A61K31/4045; C07D339/04; A61K31/405; A61K31/48; A61K45/00; A61P1/08; A61P3/02; A61P25/00; A61P25/02; A61P25/04; A61P25/06; A61P25/08; A61P39/06; A61P43/00; (IPC1-7): A61K31/385; A61P25/06
Domestic Patent References:
| WO1999051097A1 | 1999-10-14 | |||
| WO1994000135A1 | 1994-01-06 |
Foreign References:
| DE4327462A1 | 1995-02-23 | |||
| US5569670A | 1996-10-29 |
Other References:
LOW: "symptomatic treatment...", J. OF THE AM. MED. ASSOCIATION, vol. 280, no. 21, pages 1863 - 1864, XP000997203
VARIOUS: "the merck manual", 1999, MERCK RESEARCH LABORATORIES, N.J., XP002165174
GLEITER C H ET AL: "LACK OF INTERACTION BETWEEN THIOCTIC ACID, GLIBENCLAMIDE AND ACARBOSE", BRITISH JOURNAL OF CLINICAL PHARMACOLOGY,GB,BLACKWELL SCIENTIFIC PUBL, vol. 48, no. 6, 1999, pages 819 - 825, XP000908779, ISSN: 0306-5251
DATABASE WPI Section Ch Week 197924, Derwent World Patents Index; Class B05, AN 1979-45483B, XP002165175
VARIOUS: "the merck manual", 1999, MERCK RESEARCH LABORATORIES, N.J., XP002165174
GLEITER C H ET AL: "LACK OF INTERACTION BETWEEN THIOCTIC ACID, GLIBENCLAMIDE AND ACARBOSE", BRITISH JOURNAL OF CLINICAL PHARMACOLOGY,GB,BLACKWELL SCIENTIFIC PUBL, vol. 48, no. 6, 1999, pages 819 - 825, XP000908779, ISSN: 0306-5251
DATABASE WPI Section Ch Week 197924, Derwent World Patents Index; Class B05, AN 1979-45483B, XP002165175
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