Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
TREATMENT OF PERIPHERAL NEUROPATHY USING GFR(ALPHA)3 TYPE RECEPTOR AGONISTS
Document Type and Number:
WIPO Patent Application WO/2014/041179
Kind Code:
A1
Abstract:
A method of treating or preventing peripheral neuropathy in a subject determined to be in need thereof comprising: topically administering to the subject an anti-peripheral neuropathic compound acting as GFRα3 type receptor agonist.

More Like This:
JP3739704Benzophenones as inhibitors of reverse transcriptase
JP2002533422INDUSTRIAL APPLICABILITY A method of using a cyclooxygenase-2 inhibitor and an integrin antagonist as a combination therapy in the treatment of neoplasia.
WO/2020/043122QUINAZOLINE DERIVATIVES AS RIP2 KINASE INHIBITOR
Inventors:
KARELSON MATI (EE)
SAARMA MART (EE)
SELI NEINAR (EE)
Application Number:
PCT/EP2013/069184
Publication Date:
March 20, 2014
Filing Date:
September 16, 2013
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
CHEMEDEST LTD (EE)
International Classes:
A61K31/381; A61K31/415; A61K31/423; A61K31/429; A61K31/433; A61K31/4706; A61K31/473; A61K31/495; A61K31/496; A61P25/02
Domestic Patent References:
WO2011070177A22011-06-16
Foreign References:
US5108921A1992-04-28
US5354844A1994-10-11
US5416016A1995-05-16
US5459127A1995-10-17
US5521291A1996-05-28
US5543158A1996-08-06
US5547932A1996-08-20
US5583020A1996-12-10
US5591721A1997-01-07
US4426330A1984-01-17
US4534899A1985-08-13
US5013556A1991-05-07
US5213804A1993-05-25
US5227170A1993-07-13
US5264221A1993-11-23
US5356633A1994-10-18
US5395619A1995-03-07
US5417978A1995-05-23
US5462854A1995-10-31
US5469854A1995-11-28
US5512295A1996-04-30
US5527528A1996-06-18
US5534259A1996-07-09
US5543152A1996-08-06
US5556948A1996-09-17
US5580575A1996-12-03
US5595756A1997-01-21
US6287860B12001-09-11
US10867398A1998-07-01
US7182202A2002-02-08
Other References:
MICHAEL H OSSIPOV: "Growth Factors and Neuropathic Pain", CURRENT PAIN AND HEADACHE REPORTS, CURRENT SCIENCE INC, NEW YORK, vol. 15, no. 3, 16 February 2011 (2011-02-16), pages 185 - 192, XP019898125, ISSN: 1534-3081, DOI: 10.1007/S11916-011-0183-5
J. PHARMACEUTICAL SCIENCES, vol. 66, 1977, pages 1 - 19
AIRAKSINEN; SAARMA: "The GDNF family: signalling, biological functions and therapeutic value", NAT REV NEUROSCI., vol. 3, 2002, pages 383 - 94, XP008045904, DOI: doi:10.1038/nrn812
BALOH, R. H.; TANSEY, M. G.; LAMPE, P. A.; FAHRNER, T. J.; ENOMOTO, H.; SIMBURGER, K. S.; LEITNER, M. L.; ARAKI, T.; JOHNSON, E. M: "Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex", NEURON, vol. 21, 1998, pages 1291 - 1302, XP000990780, DOI: doi:10.1016/S0896-6273(00)80649-2
GARDELL L.R.; WANG R.; EHRENFELS C. ET AL.: "Multiple actions of systemic artemin in experimental neuropathy", NAT MED., vol. 9, 2003, pages 1383 - 1389, XP002434251, DOI: doi:10.1038/nm944
OSSIPOV, M.H.: "Growth Factors and Neuropathic Pain", PAIN AND HEADACHE REPORTS, vol. 15, 2011, pages 185 - 192, XP019898125, DOI: doi:10.1007/s11916-011-0183-5
WANG, R.; KING, T.; OSSIPOV, M.H. ET AL.: "Persistent restoration of sensory function by immediate or delayed systemic artemin after dorsal root injury", NAT. NEUSROSCI., vol. 11, pages 488 - 496, XP002733519, DOI: doi:10.1038/nn2069
Attorney, Agent or Firm:
SARAP, Margus (Kompanii 1C, Tartu, EE)
Download PDF:
View/Download PDF      PDF Help



 
Previous Patent: ENZYMATIC OXIDATION OF SULFIDE MINERALS

Next Patent: LIFTER AND METHOD FOR HANDLING A ROTOR BLADE, ROTOR BLADE FOR A WIND GENERATOR AND METHOD FOR MARKIN...