Title:
TREATMENT AND PREVENTION OF ALZHEIMER'S DISEASE (AD)
Document Type and Number:
WIPO Patent Application WO/2015/165980
Kind Code:
A3
Abstract:
The invention discloses a monocyte inducing agent and/or a monocyte activating agent and/or a monocyte recruiting agent for use in the treatment and prevention of AD.
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Inventors:
MANDLER MARKUS (AT)
SANTIC RADMILA (AT)
SCHNEEBERGER ACHIM (AT)
MATTNER FRANK (AT)
SCHMIDT WALTER (AT)
SANTIC RADMILA (AT)
SCHNEEBERGER ACHIM (AT)
MATTNER FRANK (AT)
SCHMIDT WALTER (AT)
Application Number:
PCT/EP2015/059364
Publication Date:
February 04, 2016
Filing Date:
April 29, 2015
Export Citation:
Assignee:
AFFIRIS AG (AT)
International Classes:
A61P25/28; A61K33/06; A61K35/15; A61K39/39
Domestic Patent References:
| WO2012055981A1 | 2012-05-03 |
Other References:
JOHANNA MAGGA ET AL: "Production of monocytic cells from bone marrow stem cells: therapeutic usage in Alzheimer's disease", JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, vol. 16, no. 5, 26 April 2012 (2012-04-26), pages 1060 - 1073, XP055143513, ISSN: 1582-1838, DOI: 10.1111/j.1582-4934.2011.01390.x
LEBSON L A ET AL: "Monocyte gene therapy in Alzheimer's disease APP+PS1 transgenic mice", CELL TRANSPLANTATION, COGNIZANT COMMUNICATION CORP, US, vol. 17, no. 4, 2008, pages 470 - 471, XP009180477, ISSN: 0963-6897
TARJA MALM ET AL: "The role and therapeutic potential of monocytic cells in Alzheimer's disease", GLIA, 12 February 2010 (2010-02-12), pages NA - NA, XP055143504, ISSN: 0894-1491, DOI: 10.1002/glia.20973
LEBSON L A ET AL: "Monocyte gene therapy in Alzheimer's disease APP+PS1 transgenic mice", CELL TRANSPLANTATION, COGNIZANT COMMUNICATION CORP, US, vol. 17, no. 4, 2008, pages 470 - 471, XP009180477, ISSN: 0963-6897
TARJA MALM ET AL: "The role and therapeutic potential of monocytic cells in Alzheimer's disease", GLIA, 12 February 2010 (2010-02-12), pages NA - NA, XP055143504, ISSN: 0894-1491, DOI: 10.1002/glia.20973
Attorney, Agent or Firm:
SONN & PARTNER PATENTANWÄLTE (Vienna, AT)
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