TREATMENT OF RHINITIS WITH ANTICHOLINERGICS ALONE IN COMBINATION WITH ANTIHISTAMINES PHOSPHODIESTERASE 4 INHIBITORS, OR CORTICOSTEROIDS

Title:

TREATMENT OF RHINITIS WITH ANTICHOLINERGICS ALONE IN COMBINATION WITH ANTIHISTAMINES PHOSPHODIESTERASE 4 INHIBITORS, OR CORTICOSTEROIDS

Document Type and Number:

WIPO Patent Application WO2005074983

Kind Code:

A3

Abstract:

The present invention provides novel combinations comprising a topical anticholinergic drug alone or in combination with topically administered antihistamines, topically or orally administered phosphodiesterase 4 inhibitors or topical corticosteroids for the treatment of rhinitis of various origins. It further comprises presentation of these combinations in locally applied formulations and includes various pharmaceutical formulations suitable for topical application, e.g. nasal sprays, nasal drops, emulsions, pastes, creams and gels.

Inventors:

MAUS JOACHIM (DE)
PETZOLD URSULA (DE)
SZELENYI ISTVAN (DE)
HOFFMANN TORSTEN (DE)
WEINGART MARIO (DE)

Application Number:

PCT/EP2005/000653

Publication Date:

April 13, 2006

Filing Date:

January 24, 2005

Export Citation:

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Assignee:

SOFOTEC GMBH & CO KG (DE)
MAUS JOACHIM (DE)
PETZOLD URSULA (DE)
SZELENYI ISTVAN (DE)
HOFFMANN TORSTEN (DE)
WEINGART MARIO (DE)

International Classes:

A61K31/401; A61K31/519; A61K31/55; A61K31/573; A61K39/00; A61K45/06; A61P11/00

Domestic Patent References:

WO2002096423A2	2002-12-05
WO2002069945A2	2002-09-12
WO2003011274A2	2003-02-13
WO2002096463A1	2002-12-05
WO2001076575A2	2001-10-18

Foreign References:

US6086914A	2000-07-11
EP1350512A1	2003-10-08
US6204285B1	2001-03-20

Other References:

FINN A F JR ET AL: "Ipratropium bromide nasal spray 0.03% provides additional relief from rhinorrhea when combined with terfenadine in perennial rhinitis patients; a randomized, double-blind, active-controlled trial", AMERICAN JOURNAL OF RHINOLOGY 1998 UNITED STATES, vol. 12, no. 6, 1998, pages 441 - 449, XP008056315, ISSN: 1050-6586

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