Title:
TRIAZINE DERIVATIVES AS LPAAT-B INHIBITORS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO2002036578
Kind Code:
A9
Abstract:
The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase beta (LPAAT- beta ) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT- beta activity.
Inventors:
BONHAM LYNN (US)
LEUNG DAVID W (US)
WHITE THAYER H (US)
KLEIN J PETER (US)
FINNEY ROBERT E (US)
HOLLENBACK DAVID M (US)
SHAFFER SCOTT A (US)
TANG NORINA M (US)
LEUNG DAVID W (US)
WHITE THAYER H (US)
KLEIN J PETER (US)
FINNEY ROBERT E (US)
HOLLENBACK DAVID M (US)
SHAFFER SCOTT A (US)
TANG NORINA M (US)
Application Number:
PCT/US2001/042837
Publication Date:
April 22, 2004
Filing Date:
October 30, 2001
Export Citation:
Assignee:
BONHAM LYNN (US)
LEUNG DAVID W (US)
WHITE THAYER H (US)
KLEIN J PETER (US)
FINNEY ROBERT E (US)
HOLLENBACK DAVID M (US)
SHAFFER SCOTT A (US)
TANG NORINA M (US)
LEUNG DAVID W (US)
WHITE THAYER H (US)
KLEIN J PETER (US)
FINNEY ROBERT E (US)
HOLLENBACK DAVID M (US)
SHAFFER SCOTT A (US)
TANG NORINA M (US)
International Classes:
A61P35/00; C07D251/50; C07D251/52; C07D251/54; (IPC1-7): C07D251/50; C07D251/52; C12N9/10; C12Q1/48; C12Q1/68; G01N33/50; A61K39/00; A61P35/00
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