Title:
TRIAZOLOPYRIDINE COMPOUNDS
Document Type and Number:
WIPO Patent Application WO2006018735
Kind Code:
A8
Abstract:
This invention is directed generally to triazolopyridine compounds that generally inhibit p38 kinase, TNF, and/or cyclooxygenase activity. Such triazolopyridine include compounds generally corresponding in structure to the following formula (I): wherein R1, R2 and R3, are as defined in this specification. This invention also is directed to compositions of such triazolopyridines (particularly pharmaceutical compositions), intermediates for the syntheses of such triazolopyridines, methods for making such triazolopyridines, and methods for treating (including preventing) conditions (typically pathological conditions) associated with p38 kinase activity, TNF activity, and/or cyclooxygenase-2 activity.
Inventors:
RUCKER PAUL V (US)
JEROME KEVIN DE WAYNE (US)
SELNESS SHAUN RAJ (US)
BALDUS JOHN EDWARD (US)
XING LI (US)
JEROME KEVIN DE WAYNE (US)
SELNESS SHAUN RAJ (US)
BALDUS JOHN EDWARD (US)
XING LI (US)
Application Number:
PCT/IB2005/002868
Publication Date:
May 04, 2006
Filing Date:
August 08, 2005
Export Citation:
Assignee:
PHARMACIA & UPJOHN CO LLC (US)
RUCKER PAUL V (US)
JEROME KEVIN DE WAYNE (US)
SELNESS SHAUN RAJ (US)
BALDUS JOHN EDWARD (US)
XING LI (US)
RUCKER PAUL V (US)
JEROME KEVIN DE WAYNE (US)
SELNESS SHAUN RAJ (US)
BALDUS JOHN EDWARD (US)
XING LI (US)
International Classes:
C07D471/04; A61K31/437
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