TRICYCLIC PYRAZOLOPYRIMIDINE DERIVATIVE

WIPO Patent Application WO/2010/098344

A1

Disclosed is a novel compound which inhibits an activity of HSP90, in particular a novel compound which inhibits a function of HSP90 as a chaperone protein and has an antitumor activity. Specifically disclosed are: a pyrazolopyrimidine compound represented by formula (1) having various substituents, which inhibits an ATPase activity of HSP90 and has an antitumor activity; an HSP90 inhibitor which contains a compound represented by formula (1); a pharmaceutical formulation which contains a compound represented by formula (1); an antitumor agent which contains a compound represented by formula (1); a pharmaceutical composition which contains a compound represented by formula (1); and a method for treating a cancer, wherein a compound represented by formula (1) is used.

WO/2020/262853	COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREFOR
JPH02180885	LACTAM DERIVATIVE
JPWO2012026433	Free crystal of tricyclic pyrazolopyrimidine derivative

OHKI HITOSHI
OKAYAMA TOORU
IKEDA MASAHIRO
OTA MASAHIRO
SHIBATA YOSHIHIRO
NAKANISHI TOSHIYUKI
UEDA YASUSI
SUZUKI NOBUYUKI
MATSUURA SHINJI

PCT/JP2010/052855

September 02, 2010

February 24, 2010

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DAIICHI SANKYO CO LTD (JP)
OHKI HITOSHI
OKAYAMA TOORU
IKEDA MASAHIRO
OTA MASAHIRO
SHIBATA YOSHIHIRO
NAKANISHI TOSHIYUKI
UEDA YASUSI
SUZUKI NOBUYUKI
MATSUURA SHINJI

C07D495/16; A61K31/519; A61P9/00; A61P25/28; A61P35/00; A61P37/06

WO2008035629A1	2008-03-27
WO2005028434A2	2005-03-31
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WO2008049105A2	2008-04-24
WO2008093075A2	2008-08-07
WO2008035629A1	2008-03-27
WO2004047755A2	2004-06-10
WO2006015263A2	2006-02-09
WO2005021568A2	2005-03-10
WO1998043991A1	1998-10-08
WO2008100447A2	2008-08-21

US20030018197A1	2003-01-23
US5250527A	1993-10-05

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ISHIBASHI Koki et al. (JP)
Kimiki Ishibashi (JP)

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