Title:
TRIPEPTIDE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/082786
Kind Code:
A1
Abstract:
Provided are a tripeptide compound, a preparation method therefor, and an application thereof. The structure of the related compound is represented by formula (I). The provided compound has angiotensin converting enzyme inhibiting bioactivity, and the compound and a pharmaceutical composition thereof play a role in preventing and treating hypertension and other cardiocerebral vascular system diseases.
Inventors:
ZHENG XIAOHUI (CN)
BAI YAJUN (CN)
QIN FANGGANG (CN)
LIU PEI (CN)
FANG JIACHENG (CN)
HE XIRUI (CN)
WANG XIAOXIAO (CN)
BAI YAJUN (CN)
QIN FANGGANG (CN)
LIU PEI (CN)
FANG JIACHENG (CN)
HE XIRUI (CN)
WANG XIAOXIAO (CN)
Application Number:
PCT/CN2015/095758
Publication Date:
June 02, 2016
Filing Date:
November 27, 2015
Export Citation:
Assignee:
UNIV NORTHWEST (CN)
International Classes:
C07K5/097; A61K38/06; A61P9/00; A61P9/12
Foreign References:
| CN1939912A | 2007-04-04 |
Other References:
LIU, HUI ET AL.: "Total Synthesis and Biological Evaluation of Grassypeptolide A", CHEM. EUR. J., vol. 19, 27 March 2013 (2013-03-27), pages 6774 - 6784, XP055446065
WANG, GUIJUN ET AL.: "Preparation of L-proline Based Aeruginosin 298-A Analogs: Optimization of the P1-moiety", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 19, 19 April 2009 (2009-04-19), pages 3798 - 3803, XP026281679
See also references of EP 3225627A4
WANG, GUIJUN ET AL.: "Preparation of L-proline Based Aeruginosin 298-A Analogs: Optimization of the P1-moiety", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 19, 19 April 2009 (2009-04-19), pages 3798 - 3803, XP026281679
See also references of EP 3225627A4
Attorney, Agent or Firm:
HENG TAI INTELLECTUAL PROPERTY AGENCY (CN)
西安恒泰知识产权代理事务所 (CN)
西安恒泰知识产权代理事务所 (CN)
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