Title:
TRIPROPEPTIN DERIVATIVE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF, AND ANTIBACTERIAL AGENT
Document Type and Number:
WIPO Patent Application WO/2012/176909
Kind Code:
A1
Abstract:
A tripropeptin derivative represented by general formula (1) or (2), or a pharmacologically acceptable salt thereof. In general formula (1), R1 represents an organic group having 1-20 carbon atoms. In general formula (2), R2 represents an organic group having 1-20 carbon atoms.
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Inventors:
HIROSAWA SEHEI (JP)
TAKAHASHI YOSHIAKI (JP)
HASHIZUME HIDEKI (JP)
KOBAYASHI YOSHIHIKO (JP)
TAKAHASHI YOSHIAKI (JP)
HASHIZUME HIDEKI (JP)
KOBAYASHI YOSHIHIKO (JP)
Application Number:
PCT/JP2012/066077
Publication Date:
December 27, 2012
Filing Date:
June 22, 2012
Export Citation:
Assignee:
MICROBIAL CHEM RES FOUND (JP)
HIROSAWA SEHEI (JP)
TAKAHASHI YOSHIAKI (JP)
HASHIZUME HIDEKI (JP)
KOBAYASHI YOSHIHIKO (JP)
HIROSAWA SEHEI (JP)
TAKAHASHI YOSHIAKI (JP)
HASHIZUME HIDEKI (JP)
KOBAYASHI YOSHIHIKO (JP)
International Classes:
C07K11/02; A61K38/00; A61P31/04; C07K7/06
Domestic Patent References:
| WO2001074850A1 | 2001-10-11 |
Other References:
HASHIZUME, H. ET AL.: "Tripropeptin C Blocks the Lipid Cycle of Cell Wall Biosynthesis by Complex Formation with Undecaprenyl Pyrophosphate.", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 55, no. 8, August 2011 (2011-08-01), pages 3821 - 3828
HASHIZUME, H. ET AL.: "Production of tripropeptins in media supplemented with precursors based on the biosynthetic pathway.", ARKIVOC, vol. 7, 2007, pages 241 - 253
HIDEKI HASHIZUME: "Biseibutsu Taisha Sanbutsu kara no Shinki Ko Kansenshoyaku no Tansaku", SYMPOSIUM ON MICROBIAL SCIENCES SYMPOSIUM PAPERS, vol. 19TH, 2007, pages 22 - 23
HASHIZUME, H. ET AL.: "A New Type of Tripropeptin with Anteiso-branched Chain Fatty Acid from Lysobacter sp. BMK333-48F3.", THE JOURNAL OF ANTIBIOTICS, vol. 61, no. 9, 2008, pages 577 - 582
HASHIZUME, H. ET AL.: "Production of tripropeptins in media supplemented with precursors based on the biosynthetic pathway.", ARKIVOC, vol. 7, 2007, pages 241 - 253
HIDEKI HASHIZUME: "Biseibutsu Taisha Sanbutsu kara no Shinki Ko Kansenshoyaku no Tansaku", SYMPOSIUM ON MICROBIAL SCIENCES SYMPOSIUM PAPERS, vol. 19TH, 2007, pages 22 - 23
HASHIZUME, H. ET AL.: "A New Type of Tripropeptin with Anteiso-branched Chain Fatty Acid from Lysobacter sp. BMK333-48F3.", THE JOURNAL OF ANTIBIOTICS, vol. 61, no. 9, 2008, pages 577 - 582
Attorney, Agent or Firm:
HIROTA, Koichi et al. (JP)
Koichi Hirota (JP)
Koichi Hirota (JP)
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Claims: