Title:
TRIPTOLIDE PRODRUGS HAVING HIGH AQUEOUS SOLUBILITY
Document Type and Number:
WIPO Patent Application WO2002070472
Kind Code:
A3
Abstract:
Compounds useful in immunosuppressive, anti-inflammatory and anticancer treatment are described. The compounds are triptolide analogs with improved water solubility and generally lower toxicity and improved pharmacokinetics compared to the parent compound.
Inventors:
DAI DONGCHENG (US)
YUAN HONGWEI (US)
MUSSER JOHN H (US)
YUAN HONGWEI (US)
MUSSER JOHN H (US)
Application Number:
PCT/US2002/006081
Publication Date:
October 24, 2002
Filing Date:
March 01, 2002
Export Citation:
Assignee:
PHARMAGENESIS INC (US)
DAI DONGCHENG (US)
YUAN HONGWEI (US)
MUSSER JOHN H (US)
DAI DONGCHENG (US)
YUAN HONGWEI (US)
MUSSER JOHN H (US)
International Classes:
C07D493/14; C07D493/20; C07D493/22; (IPC1-7): A61K31/343; C07D307/77; C07D407/14
Foreign References:
| US6150539A | 2000-11-21 |
Other References:
See also references of EP 1408957A4
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