Title:
TRITIATED PLANAR CARBON FORMS
Document Type and Number:
WIPO Patent Application WO/2011/159789
Kind Code:
A3
Abstract:
Tritiated planar carbon forms and their production are provided. Methods are provided for the stoichiometrically controlled labeling of planar carbon forms capitalizing on normal flaws of carboxylic acids ubiquitously present in commercial preparations of these planar carbon forms. Alternative methods include generation of a metallated intermediate whereby a metal is substituted for hydrogen on the carbon backbone of a planar carbon form. The metalized intermediate is then reacted with a tritium donor to covalently label the planar carbon form. The tritiated planar carbon forms produced are useful, for example, for determination of a biological property or environmental fate of planar carbon forms.
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Inventors:
FILER CRIST N (US)
Application Number:
PCT/US2011/040509
Publication Date:
April 19, 2012
Filing Date:
June 15, 2011
Export Citation:
Assignee:
PERKINELMER HEALTH SCI INC (US)
FILER CRIST N (US)
FILER CRIST N (US)
International Classes:
C01B31/02; A61K51/02; G01N23/00; G01N33/534
Foreign References:
| US20070231252A1 | 2007-10-04 | |||
| US20090147906A1 | 2009-06-11 |
Other References:
BAOJUN LIU ET AL., FUSION SCIENCE AND TECHNOLOGY., vol. 54, 2008, pages 627 - 630, XP008168324
ZHUANG LIU ET AL.: "Drug Delivery with Carbon Nanotubes for In vivo Cancer Treatment", CANCER RESEARCH, vol. 68, 2008, pages 6652 - 6660, XP055073616
ZHUANG LIU ET AL.: "Drug Delivery with Carbon Nanotubes for In vivo Cancer Treatment", CANCER RESEARCH, vol. 68, 2008, pages 6652 - 6660, XP055073616
Attorney, Agent or Firm:
GOULD, Weston R. et al. (Krass Sprinkle, Anderson & Citkowski, P.C.,2701 Troy Center Drive, Suite 330,Post Office Box 702, Troy MI, US)
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