Title:
TRYPTASE INHIBITOR
Document Type and Number:
WIPO Patent Application WO/1999/012918
Kind Code:
A1
Abstract:
Compounds represented by general formula (I) (wherein each symbol is as defined in the specification) or pharmacologically acceptable salts thereof, a pharmaceutical composition thereof, and use thereof as a pharmaceutical. The compounds and pharmacologically acceptable salts thereof have an excellent tryptase inhibitory activity, are orally administrable, and have a reduced toxicity, thus being useful for pharmaceuticals, for example, those for prophylaxis or therapy of allergic diseases and the like.
Inventors:
ONO SHINICHIRO (JP)
TAKEUCHI MASAHIRO (JP)
SAKASHITA HIROSHI (JP)
KUWAHARA SHIGEKI (JP)
NAITO KOJI (JP)
NAITO YOUICHIRO (JP)
IMAGAWA TAKASHI (JP)
TAKEUCHI MASAHIRO (JP)
SAKASHITA HIROSHI (JP)
KUWAHARA SHIGEKI (JP)
NAITO KOJI (JP)
NAITO YOUICHIRO (JP)
IMAGAWA TAKASHI (JP)
Application Number:
PCT/JP1998/003978
Publication Date:
March 18, 1999
Filing Date:
September 04, 1998
Export Citation:
Assignee:
YOSHITOMI PHARMACEUTICAL (JP)
ONO SHINICHIRO (JP)
TAKEUCHI MASAHIRO (JP)
SAKASHITA HIROSHI (JP)
KUWAHARA SHIGEKI (JP)
NAITO KOJI (JP)
NAITO YOUICHIRO (JP)
IMAGAWA TAKASHI (JP)
ONO SHINICHIRO (JP)
TAKEUCHI MASAHIRO (JP)
SAKASHITA HIROSHI (JP)
KUWAHARA SHIGEKI (JP)
NAITO KOJI (JP)
NAITO YOUICHIRO (JP)
IMAGAWA TAKASHI (JP)
International Classes:
A61K31/34; A61K31/38; A61K31/445; A61K31/54; (IPC1-7): C07D307/85; A61K31/34; A61K31/38; A61K31/445; A61K31/54; C07D333/66; C07D405/06; C07D495/04
Domestic Patent References:
| WO1995032945A1 | 1995-12-07 | |||
| WO1996009297A1 | 1996-03-28 |
Attorney, Agent or Firm:
Takashima, Hajime (Hiranomachi 3-chome Chuo-ku Osaka-shi Osaka, JP)
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