Title:
TWO- CHAMBER DUAL-PORE DEVICE
Document Type and Number:
WIPO Patent Application WO/2013/074546
Kind Code:
A8
Abstract:
Provided is a device comprising a channel through and defined by a plurality of layers surrounding the channel, the channel connecting a first and a second chambers separated by the plurality of layers, wherein the plurality of layers comprise a first layer, a second layer; and a conductive middle layer disposed between the first and second layers, wherein the channel comprises (a) a first region defined by the first layer, denoted as an inlet, that is about 0.5 nm to about 100 nm in diameter and (b) a second region defined by the second layer, denoted as an outlet, wherein the inlet and the outlet are about 10 nm to about 1000 nm apart from each other, and wherein the first and second chambers and the middle layer are connected to a power supply. Also provided are methods of preparing and using the device, in particular for nucleic acid sequencing.
Inventors:
DUNBAR WILLIAM (US)
SCHMIDT HOLGER (US)
HAWKINS AARON (US)
SCHMIDT HOLGER (US)
HAWKINS AARON (US)
Application Number:
PCT/US2012/064879
Publication Date:
June 27, 2013
Filing Date:
November 13, 2012
Export Citation:
Assignee:
UNIV CALIFORNIA (US)
UNIV BRIGHAM YOUNG (US)
DUNBAR WILLIAM (US)
SCHMIDT HOLGER (US)
HAWKINS AARON (US)
UNIV BRIGHAM YOUNG (US)
DUNBAR WILLIAM (US)
SCHMIDT HOLGER (US)
HAWKINS AARON (US)
International Classes:
C12Q1/68; B82Y35/00; G01N27/447; H01L49/00
Attorney, Agent or Firm:
BELL, Adam, Warwick et al. (58 West Portal Avenue # 121San Francisco, CA, US)
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