TYPE OF NOVEL LIPID COMPOUND AND USE THEREOF - NANJING VAZYME BIOTECH CO LTD

Title:

TYPE OF NOVEL LIPID COMPOUND AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2023/241314

Kind Code:

A1

Abstract:

The present disclosure relates to a type of novel lipid compound and a use thereof, and specifically relates to a type of novel lipid compound and to a lipid nanodelivery carrier comprising the compound; the compound has improved biocompatibility, effectively reduces the toxic side effects of nucleic acid drug lipid nanoparticles, increases the variety of ionizable lipid compounds, and provides more choices for the delivery of nucleic acid drugs.

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Inventors:

ZHANG YAN (CN)
XU XIAOYU (CN)
LI JINBO (CN)
FENG YI (CN)
KONG HAO (CN)

Application Number:

PCT/CN2023/095573

Publication Date:

December 21, 2023

Filing Date:

May 22, 2023

Export Citation:

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Assignee:

NANJING VAZYME BIOTECH CO LTD (CN)

International Classes:

C07D249/04; A61K9/51; A61K47/22; A61K48/00; C07D249/06

Domestic Patent References:

WO2017049245A2	2017-03-23
WO2017201332A1	2017-11-23
WO2020061367A1	2020-03-26
WO2022112855A1	2022-06-02

Foreign References:

CN110520409A	2019-11-29
CN113185421A	2021-07-30

Attorney, Agent or Firm:

BEYOND ATTORNEYS AT LAW (CN)

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